Ferreira M S, Nishioka S de A, Rocha A, Silva A M, Ferreira R G, Olivier W, Tostes Júnior S
Centro de Ciencias Biomedicas, Universidade Federal de Uberlandia, Brazil.
Am J Trop Med Hyg. 1991 Dec;45(6):723-7. doi: 10.4269/ajtmh.1991.45.723.
A 37-year-old hemophiliac patient with known, asymptomatic human immunodeficiency virus infection and chronic Chagas' disease was admitted to the hospital complaining of fever and headache. A computed tomographic scan revealed multiple ring-enhancing lesions in both cerebral hemispheres. No antibodies to Trypanosoma cruzi were found in the cerebrospinal fluid. Treatment for toxoplasmosis of the central nervous system, which was considered the most likely diagnosis, was instituted, but the patient died after progressive neurologic deterioration. An autopsy revealed severe meningoencephalitis caused by T. cruzi.
一名37岁的血友病患者，已知感染无症状人类免疫缺陷病毒且患有慢性恰加斯病，因发热和头痛入院。计算机断层扫描显示双侧大脑半球有多个环形强化病灶。脑脊液中未发现抗克氏锥虫抗体。考虑最可能的诊断为中枢神经系统弓形虫病，遂开始治疗，但患者在进行性神经功能恶化后死亡。尸检显示由克氏锥虫引起严重脑膜脑炎。
