Department of Medicine, University of Queensland, 4102, Brisbane, Australia.
Inflammopharmacology. 1999;7(3):303-10. doi: 10.1007/s10787-999-0014-z.
The proposed arthro-preventive action of cetyl myristoleate, an OTC product sold as a nutritional supplement, could not be confirmed, using an almost identical bioassay (adjuvant-induced polyarthritis in rats) as that described in the original report (Diehl and May, 1994) with the same, and 3 other, dosing schedules.
角鲨烯肉豆蔻酸酯作为一种非处方产品作为营养补充剂被宣传具有关节预防作用,但用几乎相同的生物测定方法(佐剂诱导的大鼠关节炎),即与原始报告(Diehl 和 May,1994)中描述的方法相同,以及另外 3 种不同的剂量方案,都无法证实其具有这种作用。