Panizzon R G
Dermatologische Universitätshautklinik, CHUV-Lausanne, Lausanne, Schweiz.
Hautarzt. 2007 Aug;58(8):701-10, quiz 711. doi: 10.1007/s00105-007-1372-3.
Dermatologic radiotherapy is based on the standard physical and radiobiological parameters. The radiation quality most often used in dermatology lies between 10 and 50 kV. Another important parameter is the half-value depth which should correspond to the depth of the tumor below the skin surface. In this way the skin is not over-exposed to radiation treatment. Indications for radiotherapy of malignant skin tumors include basal cell carcinoma, squamous cell carcinoma, severe actinic keratoses, lentigo maligna, lentigo maligna melanoma, Merkel cell carcinoma, and Kaposi sarcoma, as well as T- and B-cell lymphomas. Most patients with malignant skin tumors require life-long monitoring after radiotherapy. The most common benign lesions where radiotherapy may be indicated are eczemas, psoriasis, and keloids, but its use should be carefully weighed in these settings.
皮肤放射治疗基于标准的物理和放射生物学参数。皮肤科最常用的辐射能量介于10至50千伏之间。另一个重要参数是半价层深度，它应与肿瘤在皮肤表面以下的深度相对应。这样皮肤就不会在放射治疗中受到过度照射。恶性皮肤肿瘤放射治疗的适应症包括基底细胞癌、鳞状细胞癌、重度光化性角化病、恶性雀斑样痣、恶性雀斑样痣黑色素瘤、默克尔细胞癌、卡波西肉瘤以及T细胞和B细胞淋巴瘤。大多数恶性皮肤肿瘤患者在放疗后需要终身监测。放疗可能适用的最常见良性病变是湿疹、银屑病和瘢痕疙瘩，但在这些情况下应谨慎权衡其使用。
