Kacerovský M, Hossner P
Gynekologicko-porodnické oddĕlení nemocnice Most.
Ceska Gynekol. 2007 Apr;72(2):140-3.
Description of case report and summary of the knowledge about acute fatty liver of pregnancy.
Case report.
Department of Obstretrics and Gynecology Most.
The case of 30-year-old woman primigravida with acute fatty liver in early postpartum period. The diagnosis of AFLP was initially suggested by the typical history of prodromal as malaise, anorexia and polydypsia before the delivery and the rapid onset of deeply jaundice developed with elevated bilirubin and liver enzymes in early postpartum period.
Acute fatty liver of pregnancy is a rare, potentional fatal disease that occurs in third trimester or early postpartum period. It is thought to be caused by a disordered metabolism of fatty acids by mitochondria in the fetus, caused by deficiency in the long-chain 3-hydroxyacyl-CoA dehydrogenase.
描述病例报告并总结关于妊娠急性脂肪肝的知识。
病例报告。
妇产科多数科室。
一名30岁初产妇，在产后早期患急性脂肪肝。AFLP的诊断最初是基于分娩前前驱症状如不适、厌食和烦渴的典型病史，以及产后早期迅速出现的深度黄疸伴胆红素和肝酶升高。
妊娠急性脂肪肝是一种罕见的、潜在致命的疾病，发生在妊娠晚期或产后早期。它被认为是由胎儿线粒体中脂肪酸代谢紊乱引起的，这是由于长链3-羟基酰基辅酶A脱氢酶缺乏所致。
