Holub Karen, Camune Barbara
Louise Herrington School of Nursing, Baylor University, 3700 Worth St, Dallas, TX 75246, USA.
J Perinat Neonatal Nurs. 2015 Jan-Mar;29(1):32-40. doi: 10.1097/JPN.0000000000000076.
Acute fatty liver of pregnancy, although rare, is usually a third trimester of pregnancy occurrence that may be life threatening for both the pregnant woman and the fetus. Often, the onset resembles gastroenteritis or cholecystitis and correct diagnosis is delayed. Because it can also present with preeclampsia and eclampsia, it may be mistakenly diagnosed as hemolysis, elevated liver enzymes, low platelet syndrome. This article presents diagnostic differences between liver conditions that can complicate pregnancy and management strategies for treating and maintaining the well-being of pregnant women, fetuses, and infants who are affected by acute fatty liver of pregnancy. Early recognition and rapid intervention from antepartum diagnosis through delivery and the postpartum period are required by the nursing team and medical providers to reduce maternal and neonatal morbidity and mortality.
妊娠急性脂肪肝虽然罕见，但通常发生在妊娠晚期，对孕妇和胎儿都可能有生命危险。通常，其发病类似肠胃炎或胆囊炎，正确诊断往往会延迟。由于它也可能表现为先兆子痫和子痫，可能会被误诊为溶血、肝酶升高、血小板减少综合征。本文介绍了可能使妊娠复杂化的肝脏疾病之间的诊断差异，以及治疗和维持受妊娠急性脂肪肝影响的孕妇、胎儿和婴儿健康的管理策略。护理团队和医疗服务提供者需要从产前诊断到分娩及产后阶段进行早期识别和快速干预，以降低孕产妇和新生儿的发病率和死亡率。
