Yavuz Kivilcim, Geyik Serdar, Pamuk Almila Gulsun, Koc Osman, Saatci Isil, Cekirge H Saruhan
Department of Radiology, Hacettepe University Hospitals, Ankara, Turkey.
J Neurosurg. 2007 Jul;107(1):49-55. doi: 10.3171/JNS-07/07/0049.
Stent-assisted embolization is an alternative endovascular treatment method for wide-necked intracranial aneurysms. Currently available stents have the limitations of poor radial force, difficult delivery systems, and lack of full retrievability. The authors report on their preliminary experience with the use of a new, fully retrievable, self-expanding neurovascular stent, which has a high radial force and easy delivery system, combined with coil or Onyx embolization for the treatment of wide-necked aneurysms, including 6-month follow-up data.
Fifteen patients with 18 wide-necked intracranial aneurysms were treated using the SOLO stent system and detachable platinum coils. Aneurysms were located at the posterior communicating artery (seven lesions), midbasilar artery (one lesion), internal carotid artery (ICA) bifurcation (one lesion), ICA-ophthalmic artery segment (eight lesions), and posterior cerebral artery (one lesion). Eleven aneurysms were small, six were large, and one was giant. Only one of these aneurysms was in the acute stage of subarachnoid hemorrhage; balloon remodeling alone failed to keep the coils in the aneurysm sac.
Only one stent required retrieving and repositioning after it had been fully deployed, and retrieval was easy and successful. No thromboembolic complication, dissection/rupture, or vasospasm occured during stent placement. Follow-up angiograms obtained at 6 months posttreatment in the 18 aneurysms demonstrated that all stents were patent with no evidence of intimal hyperplasia or stenosis. In all cases but one, 100% lesion occlusion was observed at the 6-month control angiography examination. Only one aneurysm had recanalized.
The fully retrievable self-expandible SOLO stent is a feasible, secure, and effective system with a high radial force and ease of delivery in treating wide-necked intracranial aneurysms in combination with coil embolization.
支架辅助栓塞术是一种用于治疗宽颈颅内动脉瘤的血管内治疗替代方法。目前可用的支架存在径向支撑力差、输送系统困难以及缺乏完全可回收性等局限性。作者报告了他们使用一种新型、完全可回收、自膨胀神经血管支架的初步经验,该支架具有高径向支撑力和易于操作的输送系统,联合弹簧圈或Onyx栓塞术治疗宽颈动脉瘤,并提供了6个月的随访数据。
15例患有18个宽颈颅内动脉瘤的患者使用SOLO支架系统和可脱卸铂金弹簧圈进行治疗。动脉瘤位于后交通动脉(7个病变)、基底动脉中段(1个病变)、颈内动脉(ICA)分叉处(1个病变)、ICA眼动脉段(8个病变)和大脑后动脉(1个病变)。11个动脉瘤为小型,6个为大型,1个为巨大型。这些动脉瘤中只有1个处于蛛网膜下腔出血急性期;单纯球囊重塑未能将弹簧圈保留在动脉瘤腔内。
仅1个支架在完全展开后需要回收并重新定位,回收过程轻松且成功。在支架置入过程中未发生血栓栓塞并发症、夹层/破裂或血管痉挛。18个动脉瘤在治疗后6个月进行的随访血管造影显示,所有支架均通畅,无内膜增生或狭窄迹象。在除1例之外的所有病例中,6个月控制血管造影检查时观察到病变100%闭塞。只有1个动脉瘤发生了再通。
完全可回收自膨胀SOLO支架是一种可行、安全且有效的系统,在联合弹簧圈栓塞术治疗宽颈颅内动脉瘤时具有高径向支撑力且易于输送。