Kakol Palm D, Holländer P
Department of Integrative Pharmacology, AstraZeneca R&D Mölndal, Mölndal, Sweden.
Lab Anim. 2007 Jul;41(3):403-5. doi: 10.1258/002367707781282721.
The Mongolian gerbil is commonly used in medical research. Intravenous administration of compounds in gerbils is difficult as tail vein injection sites are not visible. The present study describes a method for intravenous administration into the jugular vein in Mongolian gerbil by using an 'over-the-needle' catheter under anaesthesia. The catheter penetrates the pectoral muscle and is easily inserted into the vein. The method is simple and avoids extensive surgery in the animals.
蒙古沙鼠常用于医学研究。由于尾静脉注射部位不可见,在沙鼠身上进行化合物的静脉给药很困难。本研究描述了一种在麻醉状态下通过使用“套管针”导管对蒙古沙鼠颈静脉进行静脉给药的方法。导管穿透胸肌并易于插入静脉。该方法简单,避免了动物进行广泛的手术。