Campistron Marion, Rouquette Isabelle, Courbon Fréderick, Chabbert Valérie, Rochaix Philippe, Prévot Grégoire, Laroumagne Sophie, Têtu Laurent, Didier Alain, Mazières Julien
Service de Pneumologie-Allergologie, Clinique des Voies Respiratoires, Hôpital Larrey, Chemin de Pouvourville, 31059 Toulouse Cedex, France.
Lung Cancer. 2008 Jan;59(1):133-6. doi: 10.1016/j.lungcan.2007.06.002. Epub 2007 Jul 20.
Adenoid cystic carcinoma (ACC) is a common head and neck tumor originating from salivary glands but that can also exceptionally develop in the trachea and major bronchi. ACC is generally considered as a slow-growing, low-grade malignancy with prolonged clinical course. Metastases are very unusual and recurrences are more often local. Treatment for localized ACC is surgery. We here report for the first time a case of lung ACC with a synchronous liver metastasis proved by biopsy. Moreover, we report the interest of performing a 18FDG PET-CT as both primary tumor and liver metastasis presented an intense FDG uptake. The specificity of the liver 18FDG uptake was confirmed by Glut-1 positive immunostaining. We propose that 18FDG PET-CT should be considered in the initial staging of lung ACC in selected patients.
腺样囊性癌（ACC）是一种常见的头颈部肿瘤，起源于唾液腺，但也可罕见地发生于气管和主支气管。ACC通常被认为是一种生长缓慢、低级别恶性肿瘤，临床病程较长。转移非常少见，复发多为局部复发。局限性ACC的治疗方法是手术。我们在此首次报告一例经活检证实的伴有同步肝转移的肺ACC病例。此外，我们报告了进行18FDG PET-CT的意义，因为原发肿瘤和肝转移灶均表现出强烈的FDG摄取。通过Glut-1阳性免疫染色证实了肝脏18FDG摄取的特异性。我们建议，对于部分选定的患者，在肺ACC的初始分期中应考虑进行18FDG PET-CT检查。
