Uraizee Imran, Cipriani Nicole A, Ginat Daniel T
Department of Pathology, University of Chicago, Chicago, IL, USA.
Department of Radiology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637, USA.
Head Neck Pathol. 2018 Dec;12(4):562-566. doi: 10.1007/s12105-017-0849-3. Epub 2017 Sep 6.
Adenoid cystic carcinoma in the oral cavity is an uncommon salivary gland malignancy that has a propensity for perineural spread. A high-grade variant is evidenced by an abundance of pleomorphic cells, loss of the classic biphasic epithelial-myoepithelial growth pattern, and comedonecrosis, as well as elevated Ki-67. CT and MRI can both be useful for demonstrating the extent of invasion in oral cavity-associated adenoid cystic carcinoma, which can attain the inferior alveolar nerve for perineural spread by direct invasion through the mandible. Reflecting the aggressive nature of this high-grade malignancy, FDG-PET can demonstrate hypermetabolism and can be useful for staging. These features are exemplified in this sine qua non radiology-pathology correlation article.
口腔腺样囊性癌是一种罕见的涎腺恶性肿瘤，具有沿神经周围扩散的倾向。高级别变异型表现为大量多形性细胞、经典的双相上皮-肌上皮生长模式消失、粉刺样坏死以及Ki-67升高。CT和MRI都有助于显示口腔相关腺样囊性癌的侵犯范围，该肿瘤可通过直接侵犯下颌骨而累及下牙槽神经以实现神经周围扩散。反映这种高级别恶性肿瘤的侵袭性，FDG-PET可显示代谢增高，有助于分期。这些特征在这篇必不可少的放射学-病理学相关性文章中得到了例证。
