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Cell signaling. A ciliary signaling switch.

作者信息

Christensen Søren Tvorup, Ott Carolyn Marie

机构信息

Department of Molecular Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.

出版信息

Science. 2007 Jul 20;317(5836):330-1. doi: 10.1126/science.1146180.

DOI:10.1126/science.1146180

PMID:17641189

Abstract

摘要

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Cell signaling. A ciliary signaling switch.

作者信息

Christensen Søren Tvorup, Ott Carolyn Marie

机构信息

Department of Molecular Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.

出版信息

Science. 2007 Jul 20;317(5836):330-1. doi: 10.1126/science.1146180.

DOI:10.1126/science.1146180

PMID:17641189

Abstract

摘要

相似文献

Cell signaling. A ciliary signaling switch.

Science. 2007 Jul 20;317(5836):330-1. doi: 10.1126/science.1146180.

The role of ciliary trafficking in Hedgehog receptor signaling.

Sci Signal. 2015 Jun 2;8(379):ra55. doi: 10.1126/scisignal.aaa5622.

The path to chemotaxis and transcription is smoothened.

Sci Signal. 2012 Aug 21;5(238):pe35. doi: 10.1126/scisignal.2003423.

Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells.

Sci Rep. 2015 May 20;5:10364. doi: 10.1038/srep10364.

The graded response to Sonic Hedgehog depends on cilia architecture.

Dev Cell. 2007 May;12(5):767-78. doi: 10.1016/j.devcel.2007.03.004.

Expression of hedgehog signaling molecules in Merkel cell carcinoma.

Head Neck. 2010 Mar;32(3):333-40. doi: 10.1002/hed.21191.

Patched1 regulates hedgehog signaling at the primary cilium.

Science. 2007 Jul 20;317(5836):372-6. doi: 10.1126/science.1139740.

IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.

Dev Cell. 2012 May 15;22(5):940-51. doi: 10.1016/j.devcel.2012.04.009.

Primary cilia are specialized calcium signalling organelles.

Nature. 2013 Dec 12;504(7479):311-4. doi: 10.1038/nature12833.

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.

J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82. doi: 10.1242/jcs.049676. Epub 2009 Aug 4.

引用本文的文献

Genetic Interaction of and Shapes Postnatal Craniofacial Bone.

J Dev Biol. 2022 May 11;10(2):17. doi: 10.3390/jdb10020017.

Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease.

Genes (Basel). 2021 Nov 5;12(11):1762. doi: 10.3390/genes12111762.

Gli affects the stemness and prognosis of epithelial ovarian cancer via homeobox protein NANOG.

Mol Med Rep. 2021 Feb;23(2). doi: 10.3892/mmr.2020.11767. Epub 2020 Dec 14.

Primary Cilia in Cystic Kidney Disease.

Results Probl Cell Differ. 2017;60:281-321. doi: 10.1007/978-3-319-51436-9_11.

Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells.

Sci Rep. 2015 May 20;5:10364. doi: 10.1038/srep10364.

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models.

J Am Soc Nephrol. 2014 Oct;25(10):2201-12. doi: 10.1681/ASN.2013070735. Epub 2014 Apr 3.

Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts.

Cilia. 2012 Apr 25;1(1):3. doi: 10.1186/2046-2530-1-3.

Primary cilia and aberrant cell signaling in epithelial ovarian cancer.

Cilia. 2012 Aug 10;1(1):15. doi: 10.1186/2046-2530-1-15.

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.

Blood. 2012 Dec 13;120(25):5002-13. doi: 10.1182/blood-2011-07-368142. Epub 2012 Jul 20.

Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling.

J Pathol. 2012 Jan;226(2):172-84. doi: 10.1002/path.3004. Epub 2011 Nov 21.