Semenova L A, Bulycheva I V
Arkh Patol. 2007 Mar-Apr;69(2):37-40.
Chondromyxoid fibroma is a benign chondroid tissue tumor characterized by the lobular overgrowth of stellate or elongated cells in the myxoid or chondroid intracellular matrix. There may be giant multinucleate cells. They may be encountered in any skeletal bones, mainly at the age of 20-30 years. A positive reaction with S-100 protein, d smooth muscle actin, and CD 34 was immunohistochemically detected in chondromyxoid fibroma tissue. In chondromyxoid fibroma, the prognosis is favorable. Recurrence of the tumor is observed in 15% of the surgically treated cases.
软骨黏液样纤维瘤是一种良性软骨样组织肿瘤,其特征是在黏液样或软骨样细胞内基质中出现星状或梭形细胞的小叶状过度增生。可能会有巨大的多核细胞。它可发生于任何骨骼,主要见于20至30岁的人群。免疫组织化学检测发现软骨黏液样纤维瘤组织中S-100蛋白、平滑肌肌动蛋白和CD 34呈阳性反应。软骨黏液样纤维瘤的预后良好。手术治疗的病例中,15%会出现肿瘤复发。