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1
Herpesvirus proteins: induction of nucleoside phosphotransferase activity after herpes simplex virus infection.疱疹病毒蛋白：单纯疱疹病毒感染后核苷磷酸转移酶活性的诱导
J Virol. 1976 Mar;17(3):1056-9. doi: 10.1128/JVI.17.3.1056-1059.1976.
2
Herpes simplex virus specified deoxypyrimidine kinase and the uptake of exogenous nucleosides by infected cells.单纯疱疹病毒特异性脱氧嘧啶激酶与受感染细胞对外源性核苷的摄取。
J Gen Virol. 1976 Jun;31(3):303-14. doi: 10.1099/0022-1317-31-3-303.
3
Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by herpes simplex virus type 1 and in cells infected with mutant strains of herpes simplex virus.在1型单纯疱疹病毒转化的细胞以及感染单纯疱疹病毒突变株的细胞中，嘧啶脱氧核糖核苷激酶（胸苷激酶）和胸苷酸激酶作为多功能酶的特性研究
J Virol. 1979 Jun;30(3):942-5. doi: 10.1128/JVI.30.3.942-945.1979.
4
Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel herpes simplex virus-induced enzyme.腺苷酸：脱氧胸苷5'-磷酸转移酶：一种新型单纯疱疹病毒诱导酶存在的证据。
J Gen Virol. 1981 Apr;53(Pt 2):247-55. doi: 10.1099/0022-1317-53-2-247.
5
Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.疱疹病毒对胸苷激酶和脱氧胞苷激酶活性的诱导作用。
J Gen Virol. 1974 Sep;24(3):465-80. doi: 10.1099/0022-1317-24-3-465.
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Adenosine- and ADP-phosphorylating capacity of herpes simplex virus-induced thymidine kinase enzyme complex.单纯疱疹病毒诱导的胸苷激酶酶复合物的腺苷和ADP磷酸化能力。
Intervirology. 1983;19(2):77-84. doi: 10.1159/000149341.
7
Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase activity.单纯疱疹病毒特异性脱氧嘧啶激酶活性的生化研究。
J Gen Virol. 1974 Sep;24(3):481-92. doi: 10.1099/0022-1317-24-3-481.
8
Cell-free synthesis of herpes simplex virus-coded pyrimidine deoxyribonucleoside kinase enzyme.单纯疱疹病毒编码的嘧啶脱氧核糖核苷激酶的无细胞合成
J Virol. 1977 Sep;23(3):455-60. doi: 10.1128/JVI.23.3.455-460.1977.
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Comparison of thymidine kinase activities indiced in cells productively infected with herpesvirus saimiri and herpes simplex virus.感染猴疱疹病毒和单纯疱疹病毒的细胞中诱导的胸苷激酶活性的比较。
J Gen Virol. 1982 Feb;58(Pt 2):237-49. doi: 10.1099/0022-1317-58-2-237.
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Induction of deoxypyrimidine kinase activity in human embryonic lung cells infected with varicella-zoster virus.水痘-带状疱疹病毒感染的人胚肺细胞中脱氧嘧啶激酶活性的诱导
J Virol. 1977 Mar;21(3):1232-5. doi: 10.1128/JVI.21.3.1232-1235.1977.

引用本文的文献

1
Analysis of the TK enzyme complex induced by HSV types 1 and 2 by means of isoelectric focusing and polyacrylamide gel electrophoresis.通过等电聚焦和聚丙烯酰胺凝胶电泳对1型和2型单纯疱疹病毒诱导的TK酶复合物进行分析。
Arch Virol. 1982;71(3):235-49. doi: 10.1007/BF01314875.
2
On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.关于（E）-5-（2-溴乙烯基）-2'-脱氧尿苷对疱疹病毒复制的选择性抑制机制
Proc Natl Acad Sci U S A. 1981 May;78(5):2698-702. doi: 10.1073/pnas.78.5.2698.
3
Inhibition of the herpes simplex virus-coded thymidine kinase-complex by 9-beta-D-arabinofuranosyladenine 5'-monophosphate (ara-AMP) and 9-(2-hydroxyethoxymethyl)guanine-monophosphate (acyclo-GMP).9-β-D-阿拉伯呋喃糖基腺嘌呤5'-单磷酸酯（ara-AMP）和9-（2-羟基乙氧甲基）鸟嘌呤-单磷酸酯（阿昔洛韦-GMP）对单纯疱疹病毒编码的胸苷激酶复合物的抑制作用。
Arch Virol. 1984;81(3-4):205-12. doi: 10.1007/BF01309993.
4
Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase.利用内部AUG密码子起始由编码单纯疱疹病毒特异性胸苷激酶的正常和突变基因的mRNA指导的蛋白质合成。
J Virol. 1985 Nov;56(2):512-9. doi: 10.1128/JVI.56.2.512-519.1985.

本文引用的文献

1
Modes of nucleoside phosphorylation in plants: studies on the apparent thymidine kinase and true uridine kinase of seedlings.植物中核苷磷酸化的模式：对幼苗中表观胸苷激酶和真尿苷激酶的研究
Biochim Biophys Acta. 1972 Aug 25;277(2):235-44.
2
Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase activity.单纯疱疹病毒特异性脱氧嘧啶激酶活性的生化研究。
J Gen Virol. 1974 Sep;24(3):481-92. doi: 10.1099/0022-1317-24-3-481.
3
Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.疱疹病毒对胸苷激酶和脱氧胞苷激酶活性的诱导作用。
J Gen Virol. 1974 Sep;24(3):465-80. doi: 10.1099/0022-1317-24-3-465.
4
Herpes virus-specified proteins. In: strategy of the viral genome.疱疹病毒特异性蛋白。见于：病毒基因组策略。
Ciba Found Symp. 1971:355-76.
5
A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus.感染单纯疱疹病毒的BHK - 21细胞中一种病毒特异性胸苷激酶。
Virology. 1967 Jan;31(1):120-8. doi: 10.1016/0042-6822(67)90015-3.

疱疹病毒蛋白：单纯疱疹病毒感染后核苷磷酸转移酶活性的诱导

Herpesvirus proteins: induction of nucleoside phosphotransferase activity after herpes simplex virus infection.

作者信息

Jamieson A T, Hay J, Subak-Sharpe J H

出版信息

J Virol. 1976 Mar;17(3):1056-9. doi: 10.1128/JVI.17.3.1056-1059.1976.

DOI:10.1128/JVI.17.3.1056-1059.1976
PMID:176440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC515506/
Abstract

After herpes simplex virus infection of hamster kidney cells there is an induction of nucleoside phosphotransferase activity which can utilize AMP as phosphate donor. The activity is immunologically specific for the infected cell and is induced concomitantly with the virus-coded pyrimidine deoxynucleoside kinase activity. Phosphotransferase activity is not induced in cells lacking both thymidine and deoxycytidine kinase activity.

摘要

单纯疱疹病毒感染仓鼠肾细胞后，会诱导核苷磷酸转移酶活性，该酶可利用AMP作为磷酸供体。这种活性对受感染细胞具有免疫特异性，并且与病毒编码的嘧啶脱氧核苷激酶活性同时被诱导。在缺乏胸苷激酶和脱氧胞苷激酶活性的细胞中，不会诱导磷酸转移酶活性。