非典型抗精神病药物治疗妄想性寄生虫病
Atypical antipsychotic drugs in the treatment of delusional parasitosis.
作者信息
Mercan Sibel, Altunay Ilknur Kivanc, Taskintuna Nilgun, Ogutcen Ozgur, Kayaoğlu Semra
机构信息
Sisli Etfal Research and Teaching Hospital, Istanbul, Turkey.
出版信息
Int J Psychiatry Med. 2007;37(1):29-37. doi: 10.2190/M8M5-H1G2-1257-2017.
INTRODUCTION
Delusional parasitosis (DP) is a rare delusional disorder in which patients believe that they are infected with parasites, worms, insects, or bacteria. Antipsychotics are the preferred treatment in these patients.
METHOD
Case series in which we summarize six patients with DP treated with atypical antipsychotic medications including amisulpride, olanzapine, and risperidone.
RESULTS
One patient had a myocardial infarction after being given amisulpride, and several patients did not adjust well. Parenterally administered antipsychotics, particularly risperidone, were the most effective treatment in this series of patients with DP.
CONCLUSION
Patients with DP can be difficult to treat; however, parenterally administered antipsychotics appear to produce better results in these patients.
引言
妄想性寄生虫病（DP）是一种罕见的妄想障碍，患者认为自己感染了寄生虫、蠕虫、昆虫或细菌。抗精神病药物是这些患者的首选治疗方法。
方法
病例系列，我们总结了6例接受非典型抗精神病药物（包括氨磺必利、奥氮平和利培酮）治疗的DP患者。
结果
1例患者在服用氨磺必利后发生心肌梗死，部分患者病情控制不佳。在这组DP患者中，胃肠外给予抗精神病药物，尤其是利培酮，是最有效的治疗方法。
结论
DP患者可能难以治疗；然而，胃肠外给予抗精神病药物似乎能使这些患者获得更好的治疗效果。
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