Khamseh Mohammad E, Baradaran Hamid R, Rajabali Hassan
Iran University of Medical Sciences, Tehran.
Int J Psychiatry Med. 2007;37(1):81-6. doi: 10.2190/FP64-82V3-1741-842V.
The aim of the present study was determine the rate of depression in people with diabetes in an Iranian population.
A hospital-based prospective study with a comparison group was conducted in Firozgar Teaching Hospital in Tehran, Iran. The condition of depression and relationship to diabetes was assessed among 375 individuals (206 people with diabetes and 169 without diabetes) who consecutively presented for this prospective study.
Of the total participation, 206 (54.9%) had diabetes (type 1 = 66 and type 2 = 140). Female made up 63.7% (n = 239). The mean age of entire study was 47.2 years (SD = 16.3 range, 15-87 years). Major depression was present among 71.8% of this sample with diabetes (both types; type 1 and type 2). Depression was more prevalent among women with diabetes than men (Adjusted OR = 2.1 (95% CI 1.4-3.2)). Of the 375 participants, 135 (36%) had BID scores lower than 11 and 240 (64%) had BDI scores indicating moderate to severe depression (> 16).
Diabetes appears to increase the risk of developing depression; therefore early detection and treatment intervention provide the best protective mechanisms available against the effects of depression on diabetes outcomes, and a psychological service provision for people with diabetes is needed.
本研究旨在确定伊朗人群中糖尿病患者的抑郁症发病率。
在伊朗德黑兰的菲罗兹加尔教学医院开展了一项设有对照组的基于医院的前瞻性研究。在375名连续参与此项前瞻性研究的个体（206名糖尿病患者和169名非糖尿病患者）中评估抑郁症状况及其与糖尿病的关系。
在全部参与者中，206人（54.9%）患有糖尿病（1型糖尿病66人，2型糖尿病140人）。女性占63.7%（n = 239）。整个研究的平均年龄为47.2岁（标准差 = 16.3，范围15 - 87岁）。该糖尿病样本（1型和2型）中71.8%存在重度抑郁症。糖尿病女性中的抑郁症比男性更普遍（调整后的比值比 = 2.1（95%置信区间1.4 - 3.2））。在375名参与者中，135人（36%）贝克抑郁量表得分低于11分，240人（64%）贝克抑郁量表得分表明存在中度至重度抑郁症（> 16分）。
糖尿病似乎会增加患抑郁症的风险；因此，早期检测和治疗干预提供了预防抑郁症对糖尿病结局产生影响的最佳保护机制，并且需要为糖尿病患者提供心理服务。
