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中国青岛成年人的健康状况、生活方式因素与抑郁:一项横断面研究

Health Conditions, Lifestyle Factors and Depression in Adults in Qingdao, China: A Cross-Sectional Study.

作者信息

Cui Nan, Cui Jing, Xu Xinpeng, Aslam Bilal, Bai Lan, Li Decheng, Wu Di, Ma Zhongren, Sun Jianping, Baloch Zulqarnain

机构信息

The Affiliated Hospital of Qingdao University, Qingdao, China.

Qingdao Municipal Center for Disease Control and Prevention, Qingdao Institute of Preventive Medicine, Qingdao, China.

出版信息

Front Psychiatry. 2021 May 14;12:508810. doi: 10.3389/fpsyt.2021.508810. eCollection 2021.

Abstract

Depression is a common mental illness. Previous studies suggested that health conditions and lifestyle factors were associated with depression. However, only few studies have explored the risk factors of depression in a large representative sample of the general population in the world. A population-based cross-sectional survey was conducted in the 2006 survey and 2009 survey in Qingdao, China. The participants with insufficient information were excluded: Zung score, body mass index (BMI), diabetes items, physical activity, smoking, or drinking. Finally, a total of 3,300 participants were included in this analysis. The category of depression was used in the Zung self-rating depression scale (ZSDS). The associations between different indicators of health conditions (diabetic status, BMI), lifestyle factors (physical activity, smoking, and alcohol consumption), and depression were assessed by the logistic regression model. The mean Zung scores for all participants, male participants, and female participants were 29.73 ± 7.57, 28.89 ± 7.30, 30.30 ± 7.70, respectively. In all participants, those who were pre-diabetes status (OR: 1.53, 95% CI: 1.04-2.27), and irregular physical activity (OR: 0.39, 95% CI: 0.17-0.89) had an increased risk of depression. In man, the analysis showed an increased risk of depression those with pre-diabetes (OR: 2.49, 95% CI: 1.25-4.97), previously diagnosed diabetes (OR: 4.44, 95% CI: 1.58, 12.48), and in those irregular activities (OR: 0.07, 95% CI: 0.01-0.61). In women, those who were underweight (OR: 5.66, 95% CI: 1.04-30.71) had a greater risk of depression. These results suggested that health conditions and lifestyle factors were the potential risk factors for depression. Men with pre-diabetes, previously diagnosed diabetes, and irregular activity had an increased risk for depression; women with underweight status had a higher risk for depression.

摘要

抑郁症是一种常见的精神疾病。先前的研究表明,健康状况和生活方式因素与抑郁症有关。然而,只有少数研究在世界一般人群的大型代表性样本中探讨了抑郁症的风险因素。在中国青岛进行了一项基于人群的横断面调查,该调查分别在2006年和2009年进行。排除信息不足的参与者:zung评分、体重指数(BMI)、糖尿病项目、体育活动、吸烟或饮酒情况。最终,共有3300名参与者纳入本分析。抑郁症类别采用zung自评抑郁量表(ZSDS)进行评定。通过逻辑回归模型评估健康状况(糖尿病状态、BMI)、生活方式因素(体育活动、吸烟和饮酒)与抑郁症之间的关联。所有参与者、男性参与者和女性参与者的zung评分均值分别为29.73±7.57、28.89±7.30、30.30±7.70。在所有参与者中,处于糖尿病前期状态者(比值比:1.53,95%置信区间:1.04 - 2.27)以及体育活动不规律者(比值比:0.39,95%置信区间:0.17 - 0.89)患抑郁症的风险增加。在男性中,分析显示糖尿病前期患者(比值比:2.49,95%置信区间:1.25 - 4.97)、先前诊断为糖尿病患者(比值比:4.44,95%置信区间:1.58,12.48)以及体育活动不规律者(比值比:0.07,95%置信区间:0.01 - 0.61)患抑郁症的风险增加。在女性中,体重过轻者(比值比:5.66,95%置信区间:1.04 - 30.71)患抑郁症的风险更高。这些结果表明,健康状况和生活方式因素是抑郁症的潜在风险因素。患有糖尿病前期、先前诊断为糖尿病以及体育活动不规律的男性患抑郁症的风险增加;体重过轻的女性患抑郁症的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ca/8160228/73bfe02eadfa/fpsyt-12-508810-g0001.jpg

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