Ishige Satoshi, Iwadate Yasuo, Ishikura Hiroshi, Saeki Naokatsu
Department of Neurological Surgery, Chiba University Graduate School of Medicine 1-8-1, Inohana, Chuo-ku, 260-8670 Chiba, Japan.
Neuropathology. 2007 Jun;27(3):290-4. doi: 10.1111/j.1440-1789.2007.00760.x.
We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) followed up with serial magnetic resonance images (MRI). A 45-year-old man manifested with bilateral abducens nerve palsy and meningisms. Repeated MRI revealed diffuse leptomeningeal enhancement throughout the central nervous system without intra-axial mass accompanied with the dilatation of ventricles and focally enlarged cerebral sulci. Brain biopsies showed a leptomeningeal gliomatosis. The MRI findings described here would contribute to the diagnosis of PDLG among other common diseases diffusely spreading along the leptomeningeal structures.
我们报告一例原发性弥漫性软脑膜胶质瘤病（PDLG），并通过系列磁共振成像（MRI）进行随访。一名45岁男性表现为双侧展神经麻痹和脑膜刺激征。重复MRI显示整个中枢神经系统弥漫性软脑膜强化，无轴内肿块，伴有脑室扩张和局部脑沟增宽。脑活检显示软脑膜胶质瘤病。本文描述的MRI表现将有助于在其他沿软脑膜结构弥漫性扩散的常见疾病中诊断PDLG。
