Gershbein L L, Spencer K L
Can J Comp Med Vet Sci. 1964 Jan;28(1):8-12.
Clinical chemical determinations were carried out on blood removed by cardiac puncture from 49 mink affected with Aleutian disease and 25 normal animals and the respective differences tested for statistical significance. Blood urea nitrogen, serum total protein and globulin, thymol turbidity, glutamic oxalacetic and glutamic pyruvic transaminases and amylase were definitely elevated in the affected animals whereas serum calcium, albumin and A/G ratio were depressed. No statistically significant difference was apparent between the two groups in the comparison of inorganic phosphorus, alkaline and acid phosphatases, bilirubin, total cholesterol and esters, cephalin-cholesterol flocculation (3+ in each case), sodium, potassium, chloride, CO(2)-combining power, leucine aminopeptidase and lactic dehydrogenase (means: over 2,000 u./ml.). For both the control and affected mink, the distribution of serum lactic dehydrogenase isozymes resembled that of human homologous serum hepatitis. Electrophoresis of serum proteins confirmed earlier findings of hypergammaglobulinemia in the diseased animals but a fast-moving or pre-albumin component, averaging 4% of the total protein, occurred in both the diseased and normal mink.
对通过心脏穿刺从49只患阿留申病的水貂和25只正常动物采集的血液进行临床化学测定，并对各自的差异进行统计学显著性检验。患病动物的血尿素氮、血清总蛋白和球蛋白、麝香草酚浊度、谷草转氨酶、谷丙转氨酶和淀粉酶明显升高，而血清钙、白蛋白和A/G比值降低。在比较无机磷、碱性和酸性磷酸酶、胆红素、总胆固醇和酯、脑磷脂-胆固醇絮状试验（每种情况下均为3+）、钠、钾、氯、二氧化碳结合力、亮氨酸氨肽酶和乳酸脱氢酶（平均值：超过2000单位/毫升）时，两组之间没有明显的统计学显著差异。对于对照水貂和患病水貂，血清乳酸脱氢酶同工酶的分布类似于人类同源血清性肝炎。血清蛋白电泳证实了先前关于患病动物高球蛋白血症的发现，但在患病和正常水貂中均出现了一种快速移动的或前白蛋白成分，平均占总蛋白的4%。
