Laplace Jean-Paul
Institut National de la Recherche Agronomique, 147 rue de l'Université, 75007 Paris.
Bull Acad Natl Med. 2006 Nov;190(8):1663-80; discussion 1680-2.
The number of foods bearing health and nutrition claims is growing in line with consumers' expectations. This market offers attractive prospects of profit for industry and commerce. The question is whether such foods really have health effects, and whether the general population or specific groups really benefit from their use. Specific regulations are needed to define the conditions of validation, communication and follow-up of such claims. The European Community's internal market is currently governed by a fragmented set of regulations and enforcement systems. Member states' national regulations differ in substance and application. For these reasons, the European Commission is seeking to create and adopt a common regulation. The following article considers the main stakes relating to consumers' health expectations, public health, and industrial and commercial interests, together with the origins of the concept of "functional foods". In contrast to the 'product based' approach in other cultures (Japan, North America, etc.), Europe has chosen a 'science based' approach focusing on physiological functions. In particular, Europe funded the FUFOSE program (Functional Food Science in Europe) coordinated by ILSI (International Life Science Institute). The bases of true functional food science are considered--how to identify beneficial interactions between food components and specific body functions, and to understand the underlying mechanisms in order to construct hypotheses for testing on volunteers. A methodology based on biological markers has been developed Europe then funded the PASSCLAIM program (Process for the assessment of scientific support for claims on foods) aimed at identifying relationships between a functional effect (normal or enhanced function) and a health benefit or a reduced risk of disease. Selected aspects of these 10-year programs illustrate the scientific bases for a European regulation of nutrition claims and so-called health claims (improved function and reduced risk of disease). The main points of the proposal are summarized The most important questions are the need for prior authorization of health claims, and the possible banning of any claim on some foods, due to their bad "nutritional profile". This implies that such claims will have to be firmly grounded in science. However, these restraints were contested by the European Parliament, which preferred a simple notification procedure and suppressed the reference to "nutritional profiling" for identifying good and bad foods. These recent political episodes reflect the lobbying aimed at preserving innovation and development, mainly by small companies that are unable to support the cost of heavy research files. In addition, there is no scientific agreement on how to determine the nutritional profile of a given food. However, the Council of Europe restored the initial text, which will again be examined by the European Parliament in the coming months. The author emphasizes the fine line that must be drawn between scientific accuracy and regulatory rigidity when validating nutrition claims, which consumers are only too willing to accept at face value.
带有健康和营养声称的食品数量正随着消费者的期望不断增加。这一市场为工商业提供了诱人的盈利前景。问题在于此类食品是否真的具有健康功效,以及普通大众或特定群体是否真的能从食用它们中获益。需要有具体的法规来界定此类声称的验证、宣传及后续跟进的条件。目前,欧洲共同体内部市场受一套零散的法规和执法体系所管辖。成员国的国家法规在实质内容和适用方面存在差异。出于这些原因,欧盟委员会正寻求制定并通过一项共同法规。以下文章探讨了与消费者健康期望、公共卫生以及工商业利益相关的主要利害关系,以及“功能性食品”概念的起源。与其他文化(日本、北美等)采用的“基于产品”的方法不同,欧洲选择了一种“基于科学”的方法,侧重于生理功能。特别是,欧洲资助了由国际生命科学研究所协调的FUFOSE项目(欧洲功能性食品科学)。文章探讨了真正的功能性食品科学的基础——如何识别食品成分与特定身体功能之间的有益相互作用,以及理解其潜在机制以便构建在志愿者身上进行测试的假设。欧洲已开发出一种基于生物标志物的方法,随后又资助了PASSCLAIM项目(食品声称科学支持评估程序),旨在确定一种功能效应(正常或增强功能)与健康益处或疾病风险降低之间的关系。这两个为期十年的项目的某些方面说明了欧洲对营养声称及所谓健康声称(功能改善和疾病风险降低)进行监管的科学依据。提案的要点进行了总结。最重要的问题是健康声称需要事先批准,以及由于某些食品“营养状况”不佳可能禁止对其进行任何声称。这意味着此类声称必须有坚实的科学依据。然而,欧洲议会对此类限制提出了质疑,它更倾向于采用简单的通报程序,并取消了用于识别优质和劣质食品的“营养成分分析”的提法。这些近期的政治事件反映了旨在维护创新和发展的游说活动,主要来自那些无力承担繁重研究档案成本的小公司。此外,对于如何确定特定食品的营养状况尚无科学共识。然而,欧洲理事会恢复了最初的文本,欧洲议会将在未来几个月再次对其进行审议。作者强调,在验证营养声称时,必须在科学准确性和监管严格性之间划清界限,而消费者往往很愿意照单全收。