Miyoshi Masaki, Tanabe Hirotaka, Shojo Tomohiro, Yamauchi Tomofusa, Takase Kosuke, Tabuchi Hitoshi
Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan.
Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
PLoS One. 2025 May 15;20(5):e0323625. doi: 10.1371/journal.pone.0323625. eCollection 2025.
We compared the visual performance of a monofocal intraocular lens (IOL) (ZCB00) and a rotationally asymmetric refractive IOL with +1.5 diopters near addition (Lentis Comfort LS-313 MF15) by investigating the ten-week postoperative parameters of both eyes of cataract patients who underwent bilateral implantation with one of the two IOLs within three months between 2011 and 2019. A total of 1352 eyes of 676 patients were enrolled; the ZCB00 group comprised 904 eyes of 452 patients (72.3 ± 6.8 years; females/males, 268/184), and the LS-313 MF15 group included 448 eyes of 224 patients (73.6 ± 7.0 years; females/males, 125/99). Comparisons were made with a linear mixed-effects model, strictly adjusting for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations, and pupil diameter to ensure statistical validity. The corrected distance visual acuity was significantly better, and most of the higher-order aberrations were significantly smaller in the ZCB00 group (p < 0.00068, Wald test). Contrast sensitivity with glare (6.3 degrees) and spectacle independence (near) were significantly better in the LS-313 MF15 group (p < 0.00068, Wald test).
我们通过研究2011年至2019年期间在三个月内接受双侧植入两种人工晶状体之一的白内障患者双眼术后十周的参数,比较了单焦点人工晶状体(IOL)(ZCB00)和近附加度数为+1.5屈光度的旋转非对称屈光性人工晶状体(Lentis Comfort LS-313 MF15)的视觉性能。共纳入676例患者的1352只眼;ZCB00组包括452例患者的904只眼(72.3±6.8岁;女性/男性,268/184),LS-313 MF15组包括224例患者的448只眼(73.6±7.0岁;女性/男性,125/99)。采用线性混合效应模型进行比较,并严格调整性别、年龄、主观验光球镜等效度、主观验光柱镜、角膜散光、眼轴长度、角膜高阶像差和瞳孔直径,以确保统计有效性。ZCB00组的矫正远视力明显更好,且大多数高阶像差明显更小(p<0.00068,Wald检验)。LS-313 MF15组在眩光(6.3度)下的对比敏感度和无眼镜依赖(近视力)明显更好(p<0.00068,Wald检验)。