Department of Ophthalmology, Tsukazaki Hospital, Himeji, Japan.
Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Sci Rep. 2020 Sep 23;10(1):15490. doi: 10.1038/s41598-020-72473-x.
To compare the visual performance of a monofocal intraocular lens (IOL) (ZCB00) and a multifocal IOL (ZMB00) of the same material and basic design, we evaluated postoperative parameters at 10 weeks after the last surgery in cataract patients who underwent bilateral ZCB00 or ZMB00 implantation from December 13, 2010, to July 29, 2019, with the right and left lenses implanted within 3 months of each other. The study enrolled 2,230 eyes of 1,115 patients. The monofocal group comprised 904 eyes of 452 patients (72.3 ± 6.8 years; females/males, 268/184), and the multifocal group comprised 1,326 eyes of 663 patients (67.0 ± 7.8 years; females/males, 518/145). Contrast sensitivity (4.0/2.5/1.6/1.0/0.7 degrees), contrast sensitivity with glare (1.6/1.0/0.7 degrees), and the VFQ-25 score for driving at night were significantly better in the monofocal group (p < 0.00068, Wald test). Uncorrected intermediate/near visual acuity and near spectacle independence were significantly better in the multifocal group (p < 0.00068, Wald test). The two IOL groups had different characteristics in terms of contrast sensitivity, night-time driving, uncorrected intermediate/near visual acuity and near spectacle independence.
为了比较相同材料和基本设计的单焦点人工晶状体（IOL）（ZCB00）和多焦点 IOL（ZMB00）的视觉性能，我们评估了 2010 年 12 月 13 日至 2019 年 7 月 29 日期间接受双侧 ZCB00 或 ZMB00 植入术的白内障患者术后 10 周的手术参数，其中右眼和左眼植入时间相隔 3 个月以内。该研究纳入了 2230 只眼 1115 例患者。单焦点组由 452 例患者的 904 只眼组成（72.3±6.8 岁；女性/男性，268/184），多焦点组由 663 例患者的 1326 只眼组成（67.0±7.8 岁；女性/男性，518/145）。在单焦点组，对比敏感度（4.0/2.5/1.6/1.0/0.7 度）、眩光下的对比敏感度（1.6/1.0/0.7 度）和夜间驾驶的 VFQ-25 评分显著更好（p<0.00068，Wald 检验）。多焦点组未矫正的中距离/近距离视力和近距离脱镜独立显著更好（p<0.00068，Wald 检验）。两组 IOL 在对比敏感度、夜间驾驶、未矫正中距离/近距离视力和近距离脱镜独立性方面具有不同的特征。
