Pan Pin-liang, Xu Wen-yan, Yao Jun, Tao Xiao-xia, Pei Li-jian, Jiang Yan
Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007 Jun;21(2):177-9.
To compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays.
Eighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods.
The number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5.
The results of HIV-1 viral load determination with the two methods are highly comparable.
比较使用NucliSens HIV-1 QT和Amplicor HIV-1 monitor 1.5检测法检测HIV-1载量的结果。
收集82份临床样本,并用上述两种方法测定HIV病毒载量。
NucliSens HIV-1 QT和Amplicor HIV-1 monitor 1.5获得的值相差<0.5 log10 RNA拷贝/毫升且病毒载量不可检测的样本数量占测量值的88.9%。在56份Deltalog10 VL<0.5的样本中,两种方法之间的相关系数为0.956。
两种方法测定HIV-1病毒载量的结果具有高度可比性。