Jin Zhong
State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Nat Prod Rep. 2007 Aug;24(4):886-905. doi: 10.1039/b502163b. Epub 2007 May 21.
A great number of natural products, especially alkaloids, which exhibit a range of biological activities including acetylcholinesterase inhibition and antineoplastic, cardiovascular and immunostimulatory activities, have been isolated from the plants of the Amaryllidaceae family. this review summarizes isolation, biological activity, and synthetic studies of these alkaloids. The primary biosynthetic pathways of each type of alkaloids are also proposed.
从石蒜科植物中已分离出大量天然产物，尤其是生物碱，它们具有一系列生物活性，包括乙酰胆碱酯酶抑制活性以及抗肿瘤、心血管和免疫刺激活性。本综述总结了这些生物碱的分离、生物活性及合成研究。还提出了每种生物碱的主要生物合成途径。
