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[生殖医学的当前可能性。2. 治疗程序的范围]

[Current possibilities in reproduction medicine. 2. Spectrum of therapeutic procedures].

作者信息

Strowitzki T, Korell M, Hepp H

机构信息

Klinikum Grosshadern, Universität München.

出版信息

Fortschr Med. 1991 Nov 30;109(34):693-7.

PMID:1765338
Abstract

As measures of assisted conception, GIFT, ZIFT, TV test and insemination require patent Fallopian tubes. In the majority of cases, intra-uterine insemination is attempted before the invasive methods. Intratubal gamete transfer is employed in particular in the case of infertility that has resisted treatment for years, some forms of male subfertility, and in patients with endometriosis or other forms of genital pathology. In addition, ZIFT and the TV test permit an assessment of in vitro fertilization. In the case of IVF, the classical indication of microscopically non-treatable tubal occlusion has been expanded considerably. Although GIFT is associated with a pregnancy rate of between 30 and 40%, IVF is increasingly being used in women in whom GIFT is indicated, thus avoiding the need for laparoscopy. The alternative techniques of transvaginal GIFT or transvaginal embryo transfer cannot yet be definitively evaluated for clinical routine use. In view of the wide range of therapeutic possibilities, individual counselling of the patient is an essential requirement.

摘要

作为辅助受孕的手段,配子输卵管内移植(GIFT)、合子输卵管内移植(ZIFT)、经阴道检查及授精需要通畅的输卵管。在大多数情况下,会先尝试宫内授精,再采用侵入性方法。输卵管内配子移植尤其适用于多年治疗无效的不孕症、某些男性生育力低下的情况以及患有子宫内膜异位症或其他生殖器病变的患者。此外,ZIFT和经阴道检查可对体外受精进行评估。在体外受精方面,传统的显微镜下无法治疗的输卵管阻塞指征已大幅扩展。尽管GIFT的妊娠率在30%至40%之间,但越来越多适合GIFT的女性选择体外受精,从而避免了腹腔镜检查的需要。经阴道GIFT或经阴道胚胎移植等替代技术尚未能在临床常规使用中得到明确评估。鉴于治疗可能性的广泛,对患者进行个性化咨询是一项基本要求。

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