Mello Luciano de Albuquerque, de Melo-Junior Mario Ribeiro, de Albuquerque Ana Cecília Cavalcanti, Coelho Maria Rosângela Cunha Duarte
Laboratório de Imunopatologia Keizo Asami, Recife, PE.
Rev Soc Bras Med Trop. 2007 May-Jun;40(3):290-4. doi: 10.1590/s0037-86822007000300008.
The objectives of this study were to estimate the serum prevalence of hepatitis C virus (HCV) infection in a dialysis center in the greater Recife region, and to correlate HCV serum positivity with some risk factors. Analyses were performed on 250 patients of both sexes, with ages ranging from 17 to 92 years old. Epidemiological data on these patients were obtained in order to determine the risk factors for this infection. Anti-HCV antibodies were investigated using fourth-generation ELISA. Statistically significant associations (p<0.05) were observed in relation to the risk factors of hemodialysis duration, number of blood component transfusions and time taken for transfusions. The prevalence was low (8.4%) in relation to other Brazilian studies. However, more studies in other centers are needed in order to estimate the real prevalence of HCV infection among patients undergoing hemodialysis in the State of Pernambuco.
本研究的目的是估计累西腓大区一家透析中心丙型肝炎病毒(HCV)感染的血清流行率,并将HCV血清阳性与一些风险因素相关联。对250名年龄在17至92岁之间的男女患者进行了分析。获取了这些患者的流行病学数据,以确定这种感染的风险因素。使用第四代酶联免疫吸附测定法(ELISA)检测抗HCV抗体。观察到与血液透析持续时间、血液成分输血次数和输血所用时间等风险因素存在统计学显著关联(p<0.05)。与巴西其他研究相比,该流行率较低(8.4%)。然而,为了估计伯南布哥州接受血液透析患者中HCV感染的实际流行率,还需要在其他中心开展更多研究。