Al Sahaf O S, Vega-Carrascal I, Cunningham F O, McGrath J P, Bloomfield F J
Department of General Surgery, Our Lady's Hospital, Navan, Co Meath, Ireland.
Ir J Med Sci. 2007 Sep;176(3):229-32. doi: 10.1007/s11845-007-0068-0. Epub 2007 Jul 25.
Exposure to surgical smoke during electrosurgery may be harmful to theatre personnel. This study quantified toxic compounds present and we were particularly interested in isolating toluene, ethylbenzene and xylene due to their putative carcinogenic effects.
A variety of surgical procedures were studied. Smoke samples emitted during electrosurgery were collected in charcoal tubes and analysed by gas chromatography coupled with mass spectrometry.
Surgery involving mainly thermal decomposition of adipose tissue produced greater quantities of aldehydes and lower concentrations of toluene. In contrast, smoke generated during epidermal tissue ablation produced higher levels of toluene, ethyl benzene and xylene.
This study demonstrated the presence of irritant, carcinogenic and neurotoxic compounds in electrosurgical smoke. This may have considerable implications for the health and safety of all involved in surgical practice, as exposure to these compounds pose potential risks to health.
电外科手术过程中接触手术烟雾可能对手术室工作人员有害。本研究对其中存在的有毒化合物进行了定量分析,鉴于甲苯、乙苯和二甲苯可能具有致癌作用,我们对分离出这些物质尤为感兴趣。
对多种外科手术进行了研究。用电外科手术过程中产生的烟雾样本收集于活性炭管中,并通过气相色谱-质谱联用仪进行分析。
主要涉及脂肪组织热分解的手术产生的醛类物质更多,而甲苯浓度较低。相比之下,表皮组织消融过程中产生的烟雾中甲苯、乙苯和二甲苯的含量更高。
本研究证明了电外科手术烟雾中存在刺激性、致癌性和神经毒性化合物。这可能对所有参与手术操作的人员的健康和安全产生重大影响,因为接触这些化合物会对健康构成潜在风险。