Hegazy Mohamed A F, Khater Ashraf A, Setit Ahmed E, Amin Mahmoud A, Kotb Sherif Z, Shafei Mohamed A El, Yousef Tamer F, Hussein Osama, Shabana Yousef K, Dayem Ola T Abdel
Department of Surgical Oncology, Mansoura University Hospital, El Gomhoria St., Mansoura, Egypt.
Department of General Surgery, Mansoura University Hospital, El Gomhoria St., Mansoura, Egypt.
World J Surg. 2007 Sep;31(9):1743-1750. doi: 10.1007/s00268-007-9147-7.
Minimal access surgery in the thyroid compartment has evolved considerably over the past 10 years and now takes many forms. This study examined the feasibility and reliability of minimally invasive thyroid surgery for the management of small benign thyroid lesions. A total of 68 patients with small thyroid nodules admitted to the Oncology Center of Mansoura University, Egypt, were enrolled in this prospective randomized trial. Patients were allotted to one of two procedures: minimally invasive video-assisted thyroidectomy (MIVAT) or minimally invasive open thyroidectomy using the Sofferman technique of strap muscle transection. Exclusion criteria were nodules > 4 cm, presence of thyroiditis, and thyroid gland volume > 20 ml. Preoperative diagnosis, operating time, blood loss, postoperative pain, complications, and cosmetic outcome were all evaluated. The MIVAT group included 35 patients, and the Sofferman group included 33 patients. The main preoperative pathology was a benign follicular lesion (70.5%), and the main postoperative final pathology was follicular adenoma (54.4%). The two groups were comparable regarding age, sex, and extent of thyroid surgery. Operating time was significantly longer in the MIVAT group (115.4 +/- 33.5 minutes) compared to the Sofferman group (65.6 +/- 23.7 minutes). The postoperative course was significantly less painful in the MIVAT group (p < 0.05). Although patients in the MIVAT group had smaller incisions (p < 0.05), the cosmetic outcome in the two groups was comparable. No long-term complication was encountered in either group. Two distinct approaches of minimally invasive thyroidectomy are now available and can be performed safely in selected patients. Despite some MIVAT advantages of less postoperative pain and slightly better cosmesis, minimally invasive open thyroidectomy offers an advantage of less operating time with comparable cosmetic results.
在过去10年里,甲状腺区域的微创手术有了很大发展,现在有多种形式。本研究探讨了微创甲状腺手术治疗小型良性甲状腺病变的可行性和可靠性。埃及曼苏拉大学肿瘤中心共纳入68例患有小型甲状腺结节的患者参与这项前瞻性随机试验。患者被分配到两种手术之一:微创视频辅助甲状腺切除术(MIVAT)或采用索弗曼胸骨舌骨肌横断技术的微创开放性甲状腺切除术。排除标准为结节直径>4 cm、存在甲状腺炎以及甲状腺体积>20 ml。对术前诊断、手术时间、失血量、术后疼痛、并发症及美容效果均进行了评估。MIVAT组包括35例患者,索弗曼组包括33例患者。术前主要病理类型为良性滤泡性病变(70.5%),术后主要最终病理类型为滤泡性腺瘤(54.4%)。两组在年龄、性别及甲状腺手术范围方面具有可比性。与索弗曼组(65.6±23.7分钟)相比,MIVAT组的手术时间明显更长(115.4±33.5分钟)。MIVAT组术后疼痛明显较轻(p<0.05)。虽然MIVAT组患者的切口较小(p<0.05),但两组的美容效果相当。两组均未出现长期并发症。现在有两种不同的微创甲状腺切除术方法,并且可以在选定的患者中安全实施。尽管MIVAT有术后疼痛较轻和美容效果稍好的一些优势,但微创开放性甲状腺切除术具有手术时间较短且美容效果相当的优势。