Department of Surgery, Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, 200233, China.
Surg Endosc. 2010 Oct;24(10):2393-400. doi: 10.1007/s00464-010-0960-y. Epub 2010 Feb 23.
We report on patients selected for minimally invasive video-assisted thyroidectomy (MIVAT) over a 3-year period and evaluate the feasibility and effects of this procedure.
Between March 2005 and August 2008, 300 patients (36 male, 264 female; mean age = 54.6 years) underwent MIVAT using a single central incision with an average length of 2 cm (range = 1.5-3 cm), about 2 cm above the sternal notch. Small conventional retractors and dissectors, ultrasonic scalpel, 5-mm laparoscope, and a video screen were the instruments used.
General anesthesia was used in 295 patients and regional block anesthesia in 5. MIVAT was performed successfully in 280 patients (93.3%). Conversion to open thyroidectomy with a 4-cm-long incision was required to achieve selective lymphadenectomy in 18 patients after frozen sections demonstrated differentiated thyroid carcinoma. Only two patients with benign thyroid nodules were converted because of large volume or massive hemorrhage from the upper pole vessels. Mean operative time was 35 min (range = 20-70 min) for unilateral lobectomy and 58 min (35-90 min) for bilateral thyroidectomy. No patients had wound infections, postoperative bleeding that required reoperation, permanent hypoparathyroidism, or bilateral recurrent laryngeal nerve palsy. However, permanent unilateral recurrent laryngeal nerve palsy appeared in five cases (1.7%), transient unilateral recurrent laryngeal nerve palsy in seven (2.3%), superior laryngeal nerve injury in five (1.7%), transient hypocalcemia in nine (3.0%), and mild skin burn from the ultrasonic scalpel in five (1.7%). Postoperative pain was minimal and better cosmetic results were obtained than conventional open thyroidectomy. Postoperative stay was shorter than with conventional open thyroidectomy.
MIVAT appears to be safe and feasible in patients with benign thyroid nodules, with minimal injury and excellent cosmetic results. Furthermore, after properly lengthening the skin incision, MIVAT can be used for patients with large benign thyroid nodules or even early-stage differentiated thyroid carcinoma.
我们报告了在过去 3 年中选择接受微创视频辅助甲状腺切除术(MIVAT)的患者,并评估了该手术的可行性和效果。
在 2005 年 3 月至 2008 年 8 月期间,300 例患者(男 36 例,女 264 例;平均年龄=54.6 岁)接受了 MIVAT 治疗,采用单一中央切口,长度平均为 2cm(范围=1.5-3cm),位于胸骨切迹上方约 2cm 处。使用小的常规牵开器和解剖器、超声刀、5mm 腹腔镜和视频屏幕。
295 例患者采用全身麻醉,5 例采用区域阻滞麻醉。280 例患者(93.3%)成功进行了 MIVAT。18 例冷冻切片显示分化型甲状腺癌的患者需要进行选择性淋巴结清扫术,因此转为开放甲状腺切除术,切口长 4cm。仅因上极血管大出血而需要转为双侧甲状腺切除术的 2 例患者因良性甲状腺结节体积大或大量出血而转为开放手术。单侧叶切除术的平均手术时间为 35 分钟(范围=20-70 分钟),双侧甲状腺切除术的平均手术时间为 58 分钟(35-90 分钟)。无患者发生伤口感染、需要再次手术的术后出血、永久性甲状旁腺功能减退或双侧喉返神经麻痹。然而,有 5 例(1.7%)出现永久性单侧喉返神经麻痹,7 例(2.3%)出现暂时性单侧喉返神经麻痹,5 例(1.7%)出现喉上神经损伤,9 例(3.0%)出现短暂性低钙血症,5 例(1.7%)出现超声刀引起的轻度皮肤烧伤。术后疼痛轻微,美容效果优于传统开放甲状腺切除术。术后住院时间短于传统开放甲状腺切除术。
MIVAT 似乎对良性甲状腺结节患者是安全且可行的,创伤小,美容效果好。此外,适当延长皮肤切口后,MIVAT 可用于治疗大的良性甲状腺结节甚至早期分化型甲状腺癌患者。