Suppr超能文献

微创视频辅助甲状腺切除术:2400多例手术经验总结

Minimally invasive video-assisted thyroidectomy: reflections after more than 2400 cases performed.

作者信息

Miccoli P, Biricotti M, Matteucci V, Ambrosini C E, Wu J, Materazzi G

机构信息

Department of Surgery, University of Pisa, Pisa, Italy.

Asia Institute Tele-Surgery, Show-Chwan Memorial Hospital, Changhua, Taiwan.

出版信息

Surg Endosc. 2016 Jun;30(6):2489-95. doi: 10.1007/s00464-015-4503-4. Epub 2015 Sep 3.

Abstract

BACKGROUND

The minimally invasive video-assisted approach was developed for primary hyperparathyroidism in 1997 and the year after for thyroid disease. Since then, the technique has been adopted worldwide, and indications moved from the initial benign disease to low-risk and intermediate-risk carcinoma, demonstrating a level of oncologic radicality comparable to the conventional open approach when inclusion criteria are strictly respected.

METHODS

Between 1998 and 2014, 2412 minimally invasive video-assisted thyroidectomies (MIVAT) were performed in our department. The indication for surgery in 825 patients (34.3 %) was a malignant tumor, in particular, a papillary carcinoma in 800 patients. Among them, 528 patients operated on between 2000 and 2009 had a mean complete follow-up of 7.5 (standard deviation, 2.3) years.

RESULTS

A total thyroidectomy was performed in 1788 patients (74.1 %) and a hemithyroidectomy in 564 (23.4 %). Also performed was central compartment lymphadenectomy in 31 patients (1.3 %) and parathyroidectomy for the presence of a solitary parathyroid adenoma in 29 (1.2 %). Mean duration of the procedure was 41 (standard deviation, 14) minutes. After a mean follow-up of 7. 5 years, 528 patients who underwent MIVAT for low-risk or intermediate-risk papillary carcinoma presented a cure rate of 85 % (undetectable thyroglobulin), comparable with the 80 % rate reported in patients who had undergone open thyroidectomy during the same period.

CONCLUSIONS

After a long experience and a considerable number of procedures performed in a single center, MIVAT is confirmed as a safe operation, with a complication rate comparable with open thyroidectomy. MIVAT offers a cure rate for the treatment of low-risk and intermediate-risk malignancies that is comparable with an open procedure when inclusion criteria are strictly respected.

摘要

背景

1997年,微创视频辅助手术方法被应用于原发性甲状旁腺功能亢进症的治疗,次年应用于甲状腺疾病的治疗。从那时起,这项技术在全球范围内得到采用,其适应证从最初的良性疾病扩展到低风险和中风险癌,当严格遵循纳入标准时,其肿瘤根治程度与传统开放手术相当。

方法

1998年至2014年期间,我们科室共进行了2412例微创视频辅助甲状腺切除术(MIVAT)。825例患者(34.3%)的手术适应证为恶性肿瘤,其中800例为乳头状癌。其中,2000年至2009年接受手术的528例患者平均随访7.5年(标准差为2.3年)。

结果

1788例患者(74.1%)进行了全甲状腺切除术,564例(23.4%)进行了半甲状腺切除术。31例患者(1.3%)进行了中央区淋巴结清扫术,29例(1.2%)因存在孤立性甲状旁腺腺瘤进行了甲状旁腺切除术。手术平均时长为41分钟(标准差为14分钟)。平均随访7.5年后,528例因低风险或中风险乳头状癌接受MIVAT的患者治愈率为85%(甲状腺球蛋白检测不到),与同期接受开放甲状腺切除术患者报告的80%治愈率相当。

结论

经过单一中心长期的经验积累和大量手术实践,MIVAT被证实是一种安全的手术,并发症发生率与开放甲状腺切除术相当。当严格遵循纳入标准时,MIVAT治疗低风险和中风险恶性肿瘤的治愈率与开放手术相当。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验