Karimi Zarchi Mojgan, Behtash Nadereh, Modares Gilani Mitra
Gynecologic Oncology Department, Vali-e-Asr Hospital, Imam Khomeini Hospital Complex, Keshavarz Boulevard, Tehran, Iran.
Arch Gynecol Obstet. 2008 Jan;277(1):75-8. doi: 10.1007/s00404-007-0416-3. Epub 2007 Jul 25.
The administration of bleomycin plus etoposide and cisplatin during pregnancy is rare.
We describe a case with good pregnancy outcome after exposure to these chemotherapeutic agents at the third trimester of pregnancy.
A pregnant woman with stage IIIc immature teratoma underwent surgical staging, and received two cycles of bleomycin, etoposide and cisplatin from the 29th week of pregnancy until delivery. The patient did not have any evidence of recurrence of ovarian cancer for 1.5 years. Her infant did not have any evidence of minor or major malformations, and showed normal neurological development during 1.5 years of follow-up.
孕期使用博来霉素联合依托泊苷和顺铂的情况罕见。
我们描述了一例在妊娠晚期接触这些化疗药物后获得良好妊娠结局的病例。
一名患有Ⅲc期未成熟畸胎瘤的孕妇接受了手术分期，并在妊娠29周直至分娩期间接受了两个周期的博来霉素、依托泊苷和顺铂治疗。该患者在1.5年内没有任何卵巢癌复发的迹象。她的婴儿在1.5年的随访期间没有任何轻微或严重畸形的迹象，并且神经发育正常。
