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CT静脉造影与超声在临床怀疑肺栓塞患者血栓栓塞性疾病诊断中的比较

CT venography vs ultrasound in the diagnosis of thromboembolic disease in patients with clinical suspicion of pulmonary embolism.

作者信息

Garcia-Bolado Ana, Del Cura Jose L

机构信息

Servicio de Radiodiagnóstico, Hospital Universitario Marqués de Valdecilla, Av. Marqués de Valdecilla 25, 39008, Santander, Cantabria, Spain.

出版信息

Emerg Radiol. 2007 Nov;14(6):403-9. doi: 10.1007/s10140-007-0654-5. Epub 2007 Jul 26.

DOI:10.1007/s10140-007-0654-5
PMID:17653779
Abstract

To assess the reliability of indirect computed tomography venography (CTV) in the detection of deep venous thrombosis (DVT) in patients with clinical suspicion of pulmonary embolism (PE). 235 consecutive patients with suspicion of PE underwent an imaging protocol composed of a CT pulmonary angiography (CTPA), a CTV and an ultrasound study of the deep venous system, which was considered the "gold standard." Sensitivity, specificity, and predictive values were calculated for CTV. ith CTV, 30 (12.8%) cases of DVT were detected, 9 (3.8%) of them without pulmonary embolism in CTPA, increasing the diagnosis of thromboembolic disease in 3.8%. However, six of these nine diagnoses were false positives, and CTV missed six cases of DVT. CTV rendered a sensitivity of 58.8%, specificity of 95.0%, a positive predictive value of 66.7%, and a negative predictive value of 93.2%. In patients with clinical suspicion of pulmonary embolism, ultrasound is preferred to CTV for the detection of DVT.

摘要

为评估间接计算机断层扫描静脉造影(CTV)在检测临床怀疑肺栓塞(PE)患者深静脉血栓形成(DVT)中的可靠性。235例连续怀疑PE的患者接受了由CT肺动脉造影(CTPA)、CTV和深静脉系统超声检查组成的成像方案,后者被视为“金标准”。计算了CTV的敏感性、特异性和预测值。通过CTV检测到30例(12.8%)DVT病例,其中9例(3.8%)在CTPA中无肺栓塞,使血栓栓塞性疾病的诊断增加了3.8%。然而,这9例诊断中有6例为假阳性,CTV漏诊了6例DVT。CTV的敏感性为58.8%,特异性为95.0%,阳性预测值为66.7%,阴性预测值为93.2%。在临床怀疑肺栓塞的患者中,对于DVT的检测,超声优于CTV。

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