Weidner Steffen M, Falkenhagen Jana, Maltsev Sergey, Sauerland Volker, Rinken Marian
Federal Institute for Materials Research and Testing (BAM), Dept. I Analytical Chemistry, Reference Materials, Richard-Willstaetter-Strasse 11, D-12489 Berlin, Germany.
Rapid Commun Mass Spectrom. 2007;21(16):2750-8. doi: 10.1002/rcm.3146.
The results of copolymer characterization by coupling of chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) techniques and subsequent calculation of copolymer composition using a novel software tool 'MassChrom2D' are presented. For high-resolution mass analysis copolymer samples were fractionated by means of liquid adsorption chromatography (LAC). These fractions were investigated off-line by MALDI-TOF MS. Various mono-n-butyl ethers of polyethylene oxide-polypropylene oxide copolymers (PEO-co-PPO) were investigated. As well as the copolymer composition presented in two-dimensional plots, the applied approach can give additional hints on specific structure-dependent separation conditions in chromatography.
本文介绍了通过色谱法与基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF MS）技术联用对共聚物进行表征的结果，以及随后使用新型软件工具“MassChrom2D”计算共聚物组成的情况。为了进行高分辨率质量分析，共聚物样品通过液相吸附色谱（LAC）进行分离。这些馏分通过MALDI-TOF MS进行离线研究。对聚环氧乙烷-聚环氧丙烷共聚物（PEO-co-PPO）的各种单正丁基醚进行了研究。除了二维图中呈现的共聚物组成外，所应用的方法还可以为色谱中特定的结构相关分离条件提供额外的线索。
