气相色谱-傅里叶变换红外光谱联用法定量分析木香烃内酯的化学成分

[Chemical constituents analysis of Mgrtol standardized by GC-FTIR].

作者信息

Lou Qi-zheng

机构信息

Department of Biology and Chemistry, Jinhua Education College, Jinhua 321000, China.

出版信息

Guang Pu Xue Yu Guang Pu Fen Xi. 2007 May;27(5):924-7.

PMID:17655105

Abstract

The chemical constituents of the Mgrtol standardized were analyzed by capillary gas chromatography-Fourier transform infrared spectroscopy (GC-FTIR). The relative content of each component was determined by area nomalization method. Twelve peaks were separated and were all identified by FTIR through search method. The results showed that the Mgrtol standardized mainly consists of 3 kinds of single terpenes, including 1,8-cineole, D-limonen and alpha-pinene, which account for 14.70%, 36.83% and 46.35% respectively, totaling to 97.88% of the entire compositions of the Mgrtol standardized. The results are the same as those analyzed by GC-MS. Comparing with GC-MS, the isomers of organic compounds separated by gas chromatography could be determined by GC-FTIR. So this method has wider application value. The results also provided a scientific proof for the further development of the plant.

摘要

采用毛细管气相色谱 - 傅里叶变换红外光谱联用技术（GC - FTIR）对标准化的Mgrtol化学成分进行分析。各组分的相对含量采用面积归一化法测定。分离出12个峰，并通过傅里叶变换红外光谱（FTIR）检索法对其进行了全部分离鉴定。结果表明，标准化的Mgrtol主要由3种单萜类化合物组成，包括1,8 - 桉叶素、D - 柠檬烯和α - 蒎烯，它们分别占标准化Mgrtol总成分的14.70%、36.83%和46.35%，总计占97.88%。结果与气相色谱 - 质谱联用（GC - MS）分析结果一致。与GC - MS相比，气相色谱分离出的有机化合物异构体可用GC - FTIR进行测定。因此，该方法具有更广泛的应用价值。研究结果也为该植物的进一步开发提供了科学依据。