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利用基因组学方法解析家畜(宿主)-蜱-病原体之间的相互作用。

Using genomic approaches to unravel livestock (host)-tick-pathogen interactions.

作者信息

Jensen Kirsty, de Miranda Santos Isabel K F, Glass Elizabeth J

机构信息

Division of Genetics and Genomics, Roslin Institute, Roslin, Midlothian, Edinburgh, EH25 9PS, UK.

出版信息

Trends Parasitol. 2007 Sep;23(9):439-44. doi: 10.1016/j.pt.2007.07.006. Epub 2007 Jul 26.

Abstract

Ticks and tick-borne diseases are a major constraint on livestock farming in many developing countries, which has a huge impact on their economies. Genomic information is becoming more abundant for many of the species involved, which if exploited successfully could be used to develop new control strategies. Here, we review the genomic resources that are now available and discuss how this information is currently being harnessed or can be used in the future to explore the complex interplay that occurs between livestock hosts, tick vectors and tick-borne pathogens.

摘要

蜱虫及蜱传疾病是许多发展中国家畜牧业的主要制约因素,对其经济产生巨大影响。对于许多相关物种而言,基因组信息正变得越来越丰富,如果能成功加以利用,这些信息可用于制定新的控制策略。在此,我们综述了目前可用的基因组资源,并讨论了当前如何利用这些信息,以及未来如何利用这些信息来探索家畜宿主、蜱虫媒介和蜱传病原体之间发生的复杂相互作用。

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