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在社区医院,颈动脉血管成形术和支架置入术是一种安全且持久有效的手术。

Carotid angioplasty and stenting is a safe and durable procedure in a community hospital.

作者信息

Friedell Mark L, Sandler Bryan J, Andriole Joseph G, Martin Samuel P, Cohen Michael J, Horowitz John D

机构信息

Department of Surgical Education, Orlando Regional Healthcare, Orlando, Florida, USA.

出版信息

Am Surg. 2007 Jun;73(6):543-6; discussion 546-7.

PMID:17658089
Abstract

Carotid angioplasty and stenting (CAS) has been touted as a reasonable alternative to carotid endarterectomy (CEA) for high-risk surgical candidates. Several published CAS series, primarily from academic centers, show immediate results approaching those of CEA. However, very little is known about long-term results with CAS, particularly in the community hospital setting. Therefore, we retrospectively reviewed our CAS experience. From February 1999 to July 2003, 44 consecutive patients underwent placement of 46 stents. The mean patient age was 73 years, and 57 per cent were men. Most patients were asymptomatic (74%). High-risk categories included prior CEA (71%), other anatomic risks (13%), and/or significant medical comorbidities (16%). Technical success was achieved in all 46 cases. At 30 days, there were no deaths and one stroke, giving a combined stroke/mortality of 2 per cent. Clinical follow-up was obtained on all 44 patients at a mean follow-up of 42 months. Duplex scans performed on 44 stents (96%), at a mean follow-up of 40 months, demonstrated four 60 per cent to 79 per cent recurrent stenoses. CAS in a community hospital can have a 30-day stroke/mortality equivalent to CEA. The procedure is durable, with no critical (80%-99%) carotid restenoses and no stroke or transient ischemic attacks referable to a stented carotid artery in long-term follow-up.

摘要

对于手术高风险患者,颈动脉血管成形术和支架置入术(CAS)已被视为颈动脉内膜切除术(CEA)的合理替代方案。一些已发表的CAS系列研究,主要来自学术中心,显示其即刻效果与CEA相近。然而,关于CAS的长期效果,尤其是在社区医院环境中的情况,人们了解甚少。因此,我们回顾性分析了我们的CAS经验。1999年2月至2003年7月,44例连续患者接受了46枚支架置入。患者平均年龄为73岁,57%为男性。大多数患者无症状(74%)。高风险类别包括既往CEA(71%)、其他解剖学风险(13%)和/或严重内科合并症(16%)。46例手术均取得技术成功。30天时,无死亡病例,1例发生卒中,卒中/死亡率合计为2%。对所有44例患者进行了临床随访,平均随访时间为42个月。对44枚支架(96%)进行了平均随访40个月的双功超声扫描,发现4例出现60%至79%的再狭窄。社区医院进行的CAS在30天时的卒中/死亡率与CEA相当。该手术效果持久,长期随访中无严重(80%-99%)颈动脉再狭窄,且未发生与支架置入的颈动脉相关的卒中或短暂性脑缺血发作。

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Am Surg. 2007 Jun;73(6):543-6; discussion 546-7.
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