Kheirkhah Ahmad, Casas Victoria, Blanco Gabriela, Li Wei, Hayashida Yasutaka, Chen Ying-Ting, Tseng Scheffer C G
Ocular Surface Center, Miami, FL 33173, USA.
Am J Ophthalmol. 2007 Aug;144(2):311-3. doi: 10.1016/j.ajo.2007.03.044.
To evaluate the feasibility of performing sutureless amniotic membrane transplantation (AMT) using fibrin glue for conjunctivochalasis.
Noncomparative interventional case series.
In 25 eyes of 16 patients with refractory conjunctivochalasis (CCh), AMT using fibrin glue was performed to cover the bare sclera.
The mean age was 55.2 +/- 18.5 years with nine patients (56.2%) younger than 60 years. The Tenon capsule was dissolved in all eyes. Fibrin glue was effective in securing the amniotic membrane to the sclera. For a mean follow-up of 10.6 +/- 4.3 months, all eyes achieved a smooth conjunctival surface with complete or significant improvement of symptoms in 44% and 56%, respectively. Complications included focal conjunctival inflammation in four eyes and pyogenic granuloma in one eye.
AMT using fibrin glue can be performed for refractory CCh resulting in alleviating its symptoms and signs.
评估使用纤维蛋白胶进行无缝线羊膜移植术(AMT)治疗结膜松弛症的可行性。
非对照干预性病例系列。
对16例难治性结膜松弛症(CCh)患者的25只眼,采用纤维蛋白胶进行AMT以覆盖裸露的巩膜。
平均年龄为55.2±18.5岁,9例(56.2%)患者年龄小于60岁。所有眼中的Tenon囊均已溶解。纤维蛋白胶能有效地将羊膜固定于巩膜。平均随访10.6±4.3个月,所有眼均获得光滑的结膜表面,44%和56%的患者症状分别完全或显著改善。并发症包括4只眼出现局限性结膜炎症,1只眼出现化脓性肉芽肿。
使用纤维蛋白胶的AMT可用于治疗难治性CCh,从而缓解其症状和体征。