Antelava N A, Pirtskhalaĭshvili N N, Antelava A V, Pachkoriia K Z
Georgian Med News. 2007 Jun(147):63-71.
The present review is dedicated to the problem of perioperative antimicrobial prophylaxis in urological surgery. There are considered modern guidelines for perioperative antimicrobial prophylaxis in urology. There are discussed; aims, timing, and duration of perioperative antimicrobial prophylaxis, risk factors of postoperative infections in urological surgery, pharmacological properties of major antimicrobial drugs, selection and route of administration of antibacterial agents. There are presented the recommendations of perioperative antimicrobial prophylaxis for the varies types of urological surgery, as well as, are given in detail the recommendations about clinical uses of antibiotics for the different types of urological interventions. There are concluded, that perioperative antimicrobial prophylaxis reduces risk of postoperative infections in urological surgery, but sometimes this prophylaxis is not effective and the problem of perioperative antimicrobial prophylaxis in urology is debatable at present. It is necessary continues search of optimal methods of of perioperative antimicrobial prophylaxis in urology. These review are designed for urologists and clinical pharmacologists.
本综述致力于泌尿外科手术围手术期抗菌预防问题。文中考虑了泌尿外科围手术期抗菌预防的现代指南。讨论了围手术期抗菌预防的目的、时机和持续时间、泌尿外科手术术后感染的危险因素、主要抗菌药物的药理学特性、抗菌药物的选择和给药途径。介绍了不同类型泌尿外科手术围手术期抗菌预防的建议,以及针对不同类型泌尿外科干预措施抗生素临床应用的详细建议。得出的结论是,围手术期抗菌预防可降低泌尿外科手术术后感染风险,但有时这种预防并不有效,目前泌尿外科围手术期抗菌预防问题仍有争议。有必要继续探索泌尿外科围手术期抗菌预防的最佳方法。本综述是为泌尿外科医生和临床药理学家编写的。