Srinivasan D, Shetty S, Ashworth D, Grew N, Millar B
Maxillofacial Surgery, New Cross Hospital, Wednesfield Road, Wolverhampton, WV10 0QP.
Br Dent J. 2007 Jul 28;203(2):91-2. doi: 10.1038/bdj.2007.635.
Osteonecrosis of the jaws (ONJ) associated with bisphosphonate therapy is being reported with increasing frequency all over the world. Pain may be the presenting symptom commonly associated with intra-oral bone exposure. The aetiology of this therapeutic complication is still not well understood. Three cases are presented and the management of the condition is discussed.
世界各地与双膦酸盐治疗相关的颌骨骨坏死（ONJ）报告频率日益增加。疼痛可能是与口腔内骨质暴露相关的常见症状。这种治疗并发症的病因仍未完全明确。本文介绍三例病例并讨论该病症的处理方法。
