α2b肾上腺素能受体的一个缺失变体与欧洲人和非洲人的情绪记忆有关。
A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans.
作者信息
de Quervain Dominique J-F, Kolassa Iris-Tatjana, Ertl Verena, Onyut P Lamaro, Neuner Frank, Elbert Thomas, Papassotiropoulos Andreas
机构信息
Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8032 Zürich, Switzerland.
出版信息
Nat Neurosci. 2007 Sep;10(9):1137-9. doi: 10.1038/nn1945. Epub 2007 Jul 29.
Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the alpha2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.
情绪唤起事件比中性事件更容易被回忆起来。这种现象有助于我们记住重要且可能至关重要的信息，它依赖于大脑中去甲肾上腺素能传递的激活。我们在此表明，编码α2b-肾上腺素能受体的基因ADRA2B的一个缺失变体，与健康的瑞士受试者以及经历过高度厌恶情绪情境的卢旺达内战幸存者的情绪记忆增强有关。
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