Wang Congyang, Xi Zhenfeng
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.
Chem Soc Rev. 2007 Sep;36(9):1395-406. doi: 10.1039/b608694m. Epub 2007 Mar 28.
Transition metal-mediated or -catalyzed carbon-carbon bond or carbon-heteroatom bond forming reactions are among the most powerful tools in organic synthesis. In addition, Lewis acid-mediated or -catalyzed organic transformations are widely used. In this context, an effective combination of these two powerful protocols or an efficient cooperation of transition metals with Lewis acids should open a new era in synthetic chemistry. This tutorial review summarizes representative synthetic methodologies developed in the past decades employing this co-operative effect.
过渡金属介导或催化的碳-碳键或碳-杂原子键形成反应是有机合成中最强大的工具之一。此外，路易斯酸介导或催化的有机转化也被广泛应用。在这种背景下，将这两种强大的方法有效结合，或者使过渡金属与路易斯酸高效协同，应该会开启合成化学的新纪元。本专题综述总结了过去几十年利用这种协同效应开发的代表性合成方法。
