[持续胸外负压时的一氧化碳弥散量]

[CO diffusing capacity during continuous negative extra-thoracic pressure].

作者信息

Asada M, Nakayama K, Kaneko K, Andoh T, Yamaguchi O, Usuda Y, Kudo I, Okutsu Y, Numata H

机构信息

Department of Anesthesiology, Yokohama City University School of Medicine.

出版信息

Masui. 1991 Oct;40(10):1492-4.

PMID:1766095

Abstract

Eight healthy males were studied to compare CO diffusing capacity (DLCO) during spontaneous breathing with that during continuous negative extra-thoracic pressure (CNETP). Mean DLCO was 33.0 +/- 5.1 ml.min-1.mmHg-1 during spontaneous breathing and 33.5 +/- 4.5 ml.min-1.mmHg-1 during CNETP with an end-expiratory negative extra-thoracic pressure (EENETP) of -20 cmH2O, and there was no significant difference between them (P less than 0.05). Pulmonary capillary blood volume, which was measured only in a male, was 76.7 ml during spontaneous breathing and 80.5 ml during CNETP. This change dose not seem to be significant. The results suggest that the effect of pulmonary diffusing capacity changes during EENETP on improvement of oxygenation may not be significant.

摘要

对8名健康男性进行了研究，以比较自主呼吸时与持续胸外负压（CNETP）时的一氧化碳弥散能力（DLCO）。自主呼吸时平均DLCO为33.0±5.1ml·min⁻¹·mmHg⁻¹，在CNETP且呼气末胸外负压（EENETP）为-20cmH₂O时平均DLCO为33.5±4.5ml·min⁻¹·mmHg⁻¹，两者之间无显著差异（P＜0.05）。仅对一名男性测量了肺毛细血管血容量，自主呼吸时为76.7ml，CNETP时为80.5ml。这种变化似乎不显著。结果表明，EENETP期间肺弥散能力变化对氧合改善的影响可能不显著。