Shor-Chudnovskiĭ M E, Bugaev V I, Tarapon O Iu, Mun L M
Klin Khir (1962). 1991(9):5-8.
When analysing the results of examination of 773 patients with obstructive jaundice (OJ) of benign genesis, purulent cholangitis (PC) was revealed in 323. In PC diagnosis, the ultrasound study is a valuable adjunctive method. In presence of the clinical signs of PC in patients and absence of the effect from conservative therapy, and as well in preservation of the high indices of bilirubinemia, the early operative treatment performed, as a rule, no later than 48 h after hospitalization is indicated. PC in patients with OJ is most frequently caused by choledocholithiasis. The causative agents of PC are represented by aerobic and anaerobic microorganisms, requiring the use of broad spectrum antibiotics before the operation and 6-12 h after it. Adequate restoration of bile passage and pathogenetically substantiated local influencing upon the inflammatory process in the bile ducts are tasks of operative intervention. Direct administration into the bile ducts of antibiotics and antiinflammatory preparations, in particular of quercitrol, via the external drain of the common bile duct is expedient.
在分析773例良性梗阻性黄疸（OJ）患者的检查结果时，发现323例患有化脓性胆管炎（PC）。在PC的诊断中，超声检查是一种有价值的辅助方法。当患者出现PC的临床症状且保守治疗无效，以及胆红素血症指标居高不下时，通常建议在入院后不迟于48小时进行早期手术治疗。OJ患者的PC最常见的病因是胆总管结石。PC的病原体为需氧菌和厌氧菌，术前及术后6 - 12小时需要使用广谱抗生素。充分恢复胆汁通路并对胆管炎症过程进行病因学上合理的局部干预是手术干预的任务。经胆总管外引流直接向胆管内注入抗生素和抗炎制剂，特别是槲皮醇，是适宜的。
