Kono Taro, Chan Henry H, Groff William Frederick, Sakurai Hiroyuki, Takeuchi Masaki, Yamaki Takashi, Soejima Kazutaka, Nozaki Motohiro
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Dermatol Surg. 2007 Aug;33(8):945-50. doi: 10.1111/j.1524-4725.2007.33196.x.
The 595-nm long-pulsed dye laser (LPDL) has been used for the treatment of vascular lesions, and although it is well absorbed by blood, it is also well absorbed by melanin. To utilize this device for the treatment of facial lentigines, we attached a glass window to the tip of the laser's handpiece, allowing compression of the skin during treatment. This prospective study aims to evaluate the efficacy and complications of using a LPDL delivered with compression for the treatment of facial lentigines in Asian persons.
Fifty-four Asian patients with facial lentigines were enrolled in this study. The laser settings included fluences between 9 and 13 J/cm(2) and a constant pulse duration of 1.5 ms. Cryogen spray cooling was not used.
Thirty-eight patients showed excellent results, 14 patients showed good results, and 2 patients showed fair results. Hyperpigmentation was seen in 1 patient.
LPDL delivered with the compression method is effective in the treatment of facial lentigines in Asian patients, and the side effect profile is minimal. The compression technique allows the traditional "vascular" LPDL to be used for treating a variety of pigmented lesions.
595纳米长脉冲染料激光(LPDL)已用于治疗血管性病变,尽管它能被血液很好地吸收,但也能被黑色素很好地吸收。为了将该设备用于治疗面部雀斑,我们在激光手持件的尖端安装了一个玻璃窗,以便在治疗过程中对皮肤进行压迫。这项前瞻性研究旨在评估使用带压迫的LPDL治疗亚洲人面部雀斑的疗效和并发症。
本研究纳入了54例患有面部雀斑的亚洲患者。激光设置包括9至13 J/cm²的能量密度和1.5毫秒的固定脉冲持续时间。未使用冷冻喷雾冷却。
38例患者效果极佳,14例患者效果良好,2例患者效果尚可。1例患者出现色素沉着。
采用压迫方法的LPDL对治疗亚洲患者的面部雀斑有效,且副作用极小。压迫技术使传统的“血管性”LPDL能够用于治疗多种色素沉着性病变。