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一种针对关注大小的细菌的甜味传感器。

A sweet sensor for size-conscious bacteria.

作者信息

Shiomi Daisuke, Margolin William

机构信息

Department of Microbiology and Molecular Genetics, University of Texas Medical School, 6431 Fannin Street, Houston, TX 77030, USA.

出版信息

Cell. 2007 Jul 27;130(2):216-8. doi: 10.1016/j.cell.2007.07.011.

Abstract

Bacteria, like eukaryotic cells, regulate their size by coordinating cell growth and division, growing faster and becoming larger when nutrients are more plentiful. Weart et al. (2007) now identify an enzyme in a glucolipid pathway that inhibits assembly of the key cell division protein FtsZ, but only during high nutrient conditions. Delaying cell division during rapid growth allows bacterial cells to become larger.

摘要

与真核细胞一样,细菌通过协调细胞生长和分裂来调节其大小,当营养物质更丰富时,生长得更快且变得更大。韦尔特等人(2007年)现在在一条糖脂途径中鉴定出一种酶,它会抑制关键细胞分裂蛋白FtsZ的组装,但仅在高营养条件下才会如此。在快速生长过程中延迟细胞分裂能使细菌细胞变得更大。

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