Senior Alan E
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA.
Cell. 2007 Jul 27;130(2):220-1. doi: 10.1016/j.cell.2007.07.004.
Protonmotive force produced by the electron transport chain is harnessed by the rotary molecular nanomotor ATP synthase to generate ATP. In this issue of Cell, Adachi et al. (2007), in a dazzling display of technical sophistication, now disentangle the coupling between the mechanical force generated by rotation of the ATP synthase subunits and the chemical reactions that occur simultaneously at the enzyme's three catalytic sites.
电子传递链产生的质子动力被旋转分子纳米马达ATP合酶利用来生成ATP。在本期《细胞》杂志中，安达千晶等人（2007年）以令人眼花缭乱的精湛技术，解开了ATP合酶亚基旋转产生的机械力与该酶三个催化位点同时发生的化学反应之间的偶联关系。
