2nd Physics Institute, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.
National Center for Nanoscience and Technology, No 11, BeiYiTiao Zhongguancun, Beijing 100190, China.
Chem Rev. 2023 Apr 12;123(7):3976-4050. doi: 10.1021/acs.chemrev.3c00028. Epub 2023 Mar 29.
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics, engineering, and materials science can elegantly converge. Since the original proposal of Nadrian Seeman, significant advances have been achieved in the past four decades. During this glory time, the DNA origami technique developed by Paul Rothemund further pushed the field forward with a vigorous momentum, fostering a plethora of concepts, models, methodologies, and applications that were not thought of before. This review focuses on the recent progress in DNA origami-engineered nanomaterials in the past five years, outlining the exciting achievements as well as the unexplored research avenues. We believe that the spirit and assets that Seeman left for scientists will continue to bring interdisciplinary innovations and useful applications to this field in the next decade.
DNA 纳米技术是一个独特的领域,物理学、化学、生物学、数学、工程学和材料科学可以在这里优雅地融合。自 Nadrian Seeman 的最初提议以来,在过去的四十年中已经取得了重大进展。在这段辉煌的时期,Paul Rothemund 开发的 DNA 折纸技术以强劲的势头进一步推动了该领域的发展,孕育了大量以前未曾想到的概念、模型、方法和应用。本文综述了过去五年中 DNA 折纸工程纳米材料的最新进展,概述了令人兴奋的成就以及尚未探索的研究方向。我们相信,Seeman 留给科学家的精神和资产将在未来十年继续为该领域带来跨学科创新和有用的应用。