Halter Ryan J, Hartov Alex, Paulsen Keith D
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.
Physiol Meas. 2007 Jul;28(7):S115-27. doi: 10.1088/0967-3334/28/7/S09. Epub 2007 Jun 26.
Conductivity imaging of the breast using electrical impedance tomography (EIT) is a three-dimensional (3D) problem since the induced currents are free to travel through the entire tissue volume. It is therefore necessary to determine the effect this 3D current flow has on the image reconstruction problem and to ascertain how much benefit is gained by using a more appropriate 3D model to estimate the conductivity distribution. In addition, it is important to consider how much is gained if measurements are collected from multiple circular arrays of electrodes positioned around the breast as opposed to just a single plane of electrodes. We used a 64 electrode EIT system to collect data from a series of high contrast saline phantoms to determine the benefits gained by using a 3D model and the incorporation of out-of-plane measurements. We found that it is preferable to use a 3D mesh even when looking only at a single plane through the object of interest and that this 3D mesh should extend in the axial direction at least one radius away from the plane of interest. Further, out-of-plane measurements enhance axial information and improve the quantification of reconstructed inclusions by a factor of 2.2 in the particular case presented here. These findings should ultimately be incorporated to clinical imaging with EIT when circular electrode arrays are employed.
使用电阻抗断层成像(EIT)对乳房进行电导率成像属于三维(3D)问题,因为感应电流可以在整个组织体积内自由流动。因此,有必要确定这种三维电流流动对图像重建问题的影响,并确定使用更合适的三维模型来估计电导率分布能带来多少益处。此外,重要的是要考虑,如果从围绕乳房放置的多个圆形电极阵列收集测量数据,而不是仅从单个电极平面收集数据,能获得多少增益。我们使用一个64电极的EIT系统从一系列高对比度盐水模型中收集数据,以确定使用三维模型和纳入平面外测量所带来的益处。我们发现,即使仅观察穿过感兴趣物体的单个平面,使用三维网格也是更可取的,并且这个三维网格应在轴向方向上延伸,至少距离感兴趣平面一个半径。此外,平面外测量增强了轴向信息,并在本文所呈现的特定情况下将重建内含物的量化提高了2.2倍。当使用圆形电极阵列时,这些发现最终应纳入EIT临床成像中。