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使用生物阻抗测量法监测接受静脉利尿剂治疗的慢性心力衰竭患者的肺液含量。

Monitoring lung fluid content in CHF patients under intravenous diuretics treatment using bio-impedance measurements.

作者信息

Freimark D, Arad M, Sokolover R, Zlochiver S, Abboud S

机构信息

Department of Cardiology, Sheba Medical Center, Ramat-Gan, Israel.

出版信息

Physiol Meas. 2007 Jul;28(7):S269-77. doi: 10.1088/0967-3334/28/7/S20. Epub 2007 Jun 26.

Abstract

A pulmonary edema monitoring system (PulmoTrace, CardioInspect, Tel-Aviv University, Israel) was evaluated for tracking lung resistivity during diuretics treatment in congestive heart failure (CHF) patients. The system incorporates a bio-impedance measurement algorithm and enables, by employing an eight-electrode thoracic belt, the assessment of both the left- and right-lung resistivity values. A clinical study was conducted on a group of 13 CHF patients under intravenous diuretics treatment. The group was measured twice-before the beginning of treatment and following a period of a couple of hours. An increase of 8% of the mean lung resistivity (median value) was found between the two measuring sessions, which indicates a dehydration of the lungs, and a significant correlation (R=0.73, p=0.004) was found between the lung resistivity change and the urine output. In conjunction with previously reported results, which demonstrated the system's reproducibility and long-term monitoring capabilities, this study further supports the diagnostics value of the system.

摘要

对一种肺水肿监测系统(以色列特拉维夫大学的PulmoTrace,CardioInspect)进行了评估,以跟踪充血性心力衰竭(CHF)患者在利尿剂治疗期间的肺电阻抗。该系统采用了生物阻抗测量算法,并通过使用八电极胸带,能够评估左肺和右肺的电阻抗值。对一组13名接受静脉利尿剂治疗的CHF患者进行了一项临床研究。在治疗开始前和经过几个小时的一段时间后对该组患者进行了两次测量。在两次测量之间发现平均肺电阻抗(中位数)增加了8%,这表明肺部出现脱水,并且在肺电阻抗变化与尿量之间发现了显著相关性(R=0.73,p=0.004)。结合先前报道的证明该系统可重复性和长期监测能力的结果,本研究进一步支持了该系统的诊断价值。

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