Tsui Po-Hsiang, Lin Lian-Yu, Chang Chien-Chung, Hwang Juey-Jen, Lin Jen-Jen, Chu Chin-Chou, Chen Chiung-Nien, Chang King-Jen, Chang Chien-Cheng
Division of Mechanics, Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan, Republic of China.
Physiol Meas. 2007 Aug;28(8):803-12. doi: 10.1088/0967-3334/28/8/004. Epub 2007 Jul 6.
Augmentation index (AIx) calculated from the pressure waveform of an artery is widely used to quantify the arterial stiffness and evaluate the cardiovascular risk. The key for calculating AIx is to locate the inflection point on the waveform signal, which is caused by the wave reflection. This study applies the probability distribution of the pressure waveform to identify the inflection point for estimating AIx. The results show that the pulse wave probability analysis not only can estimate AIx with a better tolerance of noise interference, but also allows for simultaneously monitoring, locating and characterizing other physiologically significant points on the pressure waveform.
根据动脉压力波形计算得出的增强指数（AIx）被广泛用于量化动脉僵硬度和评估心血管风险。计算AIx的关键在于确定波形信号上由波反射引起的拐点。本研究应用压力波形的概率分布来识别拐点以估计AIx。结果表明，脉搏波概率分析不仅能够在对噪声干扰具有更好耐受性的情况下估计AIx，还能同时监测、定位和表征压力波形上其他具有生理意义的点。
