Rocha Eduardo Arrais, Gondim Tatiana Pereira, Abreu Sebastião, Farias Roberto, Marques Vera, Rocha Almino, Ribeiro Demóstenes, Pereira Ricardo, Negreiros Pedro, Rodrigues Carlos Roberto M, Paes José Nogueira
Hospital das Clínicas da Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Arq Bras Cardiol. 2007 Jun;88(6):674-82. doi: 10.1590/s0066-782x2007000600008.
To analyze the conventional biventricular pacing (BV) and the bifocal (BF) right ventricular (RV) pacing, and to perform a comparative analysis of these two techniques in relation to clinical, functional and echocardiographic parameters in a population without the exclusion criteria of the major studies.
A prospective non-randomized analysis of 36 patients undergoing surgery for multisite pacemaker implantation due to QRS > or =130 ms, severe left ventricular dysfunction, and NYHA functional class III or ambulatory class IV congestive heart failure was performed.
Favorable results of resynchronization were obtained with both techniques, with no significant differences in the comparison of the two groups, except for a higher QRS narrowing in the BV group, and a trend of a lower number or hospital admissions in the BV group. When the groups were analyzed separately and compared before and after the procedures, we observed that improvement was much more significant in the biventricular group, as were the more statistically relevant rates.
Cardiac resynchronization therapy proved to be an efficient therapy in both groups analyzed, although with more significant outcomes in the biventricular group.
分析传统双心室起搏(BV)和双焦点(BF)右心室(RV)起搏,并在无主要研究排除标准的人群中,针对临床、功能和超声心动图参数对这两种技术进行比较分析。
对36例因QRS≥130 ms、严重左心室功能不全以及纽约心脏协会(NYHA)心功能Ⅲ级或动态心功能Ⅳ级充血性心力衰竭而接受多部位起搏器植入手术的患者进行前瞻性非随机分析。
两种技术均获得了良好的再同步化效果,两组比较无显著差异,但BV组的QRS缩窄更明显,且BV组的住院次数有降低趋势。当分别分析两组并比较手术前后情况时,我们观察到双心室组的改善更为显著,统计学相关率也是如此。
心脏再同步化治疗在分析的两组中均被证明是一种有效的治疗方法,尽管双心室组的结果更显著。