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多动症和抽动障碍患儿的药物及非药物治疗

Drug and non-drug treatments of children with ADHD and tic disorders.

作者信息

Poncin Yann, Sukhodolsky Denis G, McGuire Joseph, Scahill Lawrence

机构信息

Child Study Center, Yale University, P.O. Box 207900, New Haven, CT, 06520, USA.

出版信息

Eur Child Adolesc Psychiatry. 2007 Jun;16 Suppl 1:78-88. doi: 10.1007/s00787-007-1010-8.

Abstract

OBJECTIVE

To review the treatment of ADHD in children with chronic tic disorders.

BACKGROUND

Tic disorders are relatively common in school-age children and range from mild to severe. Children with mild tics may not require medication for the treatment of tics. The co-occurrence of attention deficit hyperactivity disorder (ADHD) and disruptive behavior are common in children with tic disorders and may be associated with significant morbidity.

METHODS

We conducted a literature search to identify reports of tics as an adverse effect to stimulant medication, the treatment of children with ADHD and tics as well as novel treatments that have been proposed for the treatment of ADHD in children with tic disorders.

RESULTS

The preponderance of evidence suggests that stimulant medications are safe and effective in the treatment of children with ADHD and tic disorders. A minority of children with tic disorders may show a worsening of tics or not tolerate stimulants for other reasons. The growing list of non-stimulants provides options for clinicians and parents of these children.

CONCLUSIONS

Treatment planning for children with ADHD and tic disorders involves careful discussion with parents on choosing the best course of action. Stimulants should be part of this discussion. More study is needed on non-pharmacological approaches to the treatment of tics and ADHD in this population.

摘要

目的

综述慢性抽动障碍儿童注意力缺陷多动障碍(ADHD)的治疗。

背景

抽动障碍在学龄儿童中相对常见,程度从轻到重不等。轻度抽动的儿童可能无需药物治疗抽动症状。注意力缺陷多动障碍(ADHD)与破坏性行为在抽动障碍儿童中共同出现很常见,且可能与显著的发病率相关。

方法

我们进行了文献检索,以确定关于抽动作为兴奋剂药物不良反应的报告、ADHD合并抽动儿童的治疗以及针对抽动障碍儿童ADHD提出的新治疗方法。

结果

大量证据表明,兴奋剂药物在治疗ADHD合并抽动障碍儿童方面是安全有效的。少数抽动障碍儿童可能会出现抽动症状加重或因其他原因不耐受兴奋剂。越来越多的非兴奋剂药物为这些儿童的临床医生和家长提供了选择。

结论

ADHD合并抽动障碍儿童的治疗计划需要与家长仔细讨论以选择最佳行动方案。兴奋剂应纳入此讨论范围。对于该人群抽动和ADHD的非药物治疗方法,还需要更多研究。

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